ZYME

Zymeworks Inc.

Insider trading activity for Zymeworks Inc., straight from SEC Form 4 filings. Net figures below count open-market buys and sales only — grants, option exercises and tax withholding are excluded because they are compensation, not decisions to trade.

Past 3 months

net buying

Bought(0 · 0 insiders): $0
Sold(0 · 0 insiders): $0

Past 6 months

net buying

Bought(0 · 0 insiders): $0
Sold(0 · 0 insiders): $0

Past 12 months

-$4.7M

net selling

Bought(0 · 0 insiders): $0
Sold(10 · 4 insiders): $4.7M

Transaction history

The 76 most recent Form 4 transactions.

Open in screener →

Insider transactions, newest first: date, security, transaction type, size and a link to the filing each row came from.
Date	Insider	Role	Type	Shares	Price	Value	Δ Own	Filing
Jul 6	Hollywood Mark	EVP & Chief Operating…	AGRANT	939	$22.22	$20.9K	+0.7%	Open the original filing on SEC.gov
May 13	Schneider Paul R	EVP, General Counsel	AGRANT◆	119,000	—	—	—	Open the original filing on SEC.gov
May 13	Schneider Paul R	EVP, General Counsel	AGRANT◆	178,000	—	—	—	Open the original filing on SEC.gov
Apr 9	Schayowitz Adam	See Remarks	AGRANT◆	76,000	—	—	—	Open the original filing on SEC.gov
Apr 9	Schayowitz Adam	See Remarks	AGRANT◆	47,000	—	—	—	Open the original filing on SEC.gov
Apr 9	Schayowitz Adam	See Remarks	AGRANT◆	70,000	—	—	—	Open the original filing on SEC.gov
Apr 9	Platshon Scott	EVP, Chief Business…	AGRANT◆	76,000	—	—	—	Open the original filing on SEC.gov
Apr 9	Platshon Scott	EVP, Chief Business…	AGRANT◆	47,000	—	—	—	Open the original filing on SEC.gov
Apr 9	Platshon Scott	EVP, Chief Business…	AGRANT◆	70,000	—	—	—	Open the original filing on SEC.gov
Apr 6	Stafford Kristin	EVP, Chief Financial…	AGRANT◆	50,000	—	—	—	Open the original filing on SEC.gov
Apr 6	Stafford Kristin	EVP, Chief Financial…	AGRANT◆	119,000	—	—	—	Open the original filing on SEC.gov
Apr 6	Stafford Kristin	EVP, Chief Financial…	AGRANT◆	178,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Smith Jeffrey T L	EVP & Chief Medical…	MEXER◆	17,666	—	—	—	Open the original filing on SEC.gov
Jan 12	Smith Jeffrey T L	EVP & Chief Medical…	SSELL	9,310	$22.67	$211.1K	-25.9%	Open the original filing on SEC.gov
Jan 12	Smith Jeffrey T L	EVP & Chief Medical…	MEXER	17,666	—	—	+96.3%	Open the original filing on SEC.gov
Jan 12	Neu Kelvin	Director	AGRANT◆	7,700	—	—	—	Open the original filing on SEC.gov
Jan 12	Neu Kelvin	Director	AGRANT◆	11,500	—	—	—	Open the original filing on SEC.gov
Jan 12	Moore Paul Andrew	Chief Scientific Officer	AGRANT◆	66,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Moore Paul Andrew	Chief Scientific Officer	AGRANT◆	47,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Moore Paul Andrew	Chief Scientific Officer	AGRANT◆	70,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Moore Paul Andrew	Chief Scientific Officer	MEXER◆	17,666	—	—	—	Open the original filing on SEC.gov
Jan 12	Moore Paul Andrew	Chief Scientific Officer	SSELL	9,560	$22.67	$216.8K	-16.5%	Open the original filing on SEC.gov
Jan 12	Moore Paul Andrew	Chief Scientific Officer	MEXER	17,666	—	—	+43.7%	Open the original filing on SEC.gov
Jan 12	Mahony Susan	Director	AGRANT◆	7,700	—	—	—	Open the original filing on SEC.gov
Jan 12	Mahony Susan	Director	AGRANT◆	11,500	—	—	—	Open the original filing on SEC.gov
Jan 12	Landry Robert E	Director	AGRANT◆	7,700	—	—	—	Open the original filing on SEC.gov
Jan 12	Landry Robert E	Director	AGRANT◆	11,500	—	—	—	Open the original filing on SEC.gov
Jan 12	Galbraith Kenneth	Chair & CEO	AGRANT◆	222,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Galbraith Kenneth	Chair & CEO	AGRANT◆	144,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Galbraith Kenneth	Chair & CEO	AGRANT◆	216,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Galbraith Kenneth	Chair & CEO	MEXER◆	64,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Galbraith Kenneth	Chair & CEO	SSELL	30,424	$22.67	$689.8K	-11.8%	Open the original filing on SEC.gov
Jan 12	Galbraith Kenneth	Chair & CEO	MEXER	64,000	—	—	+33.1%	Open the original filing on SEC.gov
Jan 12	Ciongoli Gregory Austin	Director	AGRANT◆	7,700	—	—	—	Open the original filing on SEC.gov
Jan 12	Ciongoli Gregory Austin	Director	AGRANT◆	11,500	—	—	—	Open the original filing on SEC.gov
Jan 12	Cesano Alessandra	Director	AGRANT◆	7,700	—	—	—	Open the original filing on SEC.gov
Jan 12	Cesano Alessandra	Director	AGRANT◆	11,500	—	—	—	Open the original filing on SEC.gov
Jan 12	Campoy Carlos	Director	AGRANT◆	7,700	—	—	—	Open the original filing on SEC.gov
Jan 12	Campoy Carlos	Director	AGRANT◆	11,500	—	—	—	Open the original filing on SEC.gov
Jan 12	Hollywood Mark	EVP & Chief Operating…	AGRANT◆	66,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Hollywood Mark	EVP & Chief Operating…	AGRANT◆	47,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Hollywood Mark	EVP & Chief Operating…	AGRANT◆	70,000	—	—	—	Open the original filing on SEC.gov
Jan 12	Hollywood Mark	EVP & Chief Operating…	MEXER◆	17,666	—	—	—	Open the original filing on SEC.gov
Jan 12	Hollywood Mark	EVP & Chief Operating…	SSELL	6,120	$22.67	$138.8K	-4.4%	Open the original filing on SEC.gov
Jan 12	Hollywood Mark	EVP & Chief Operating…	MEXER	17,666	—	—	+14.6%	Open the original filing on SEC.gov
Jan 12	Cherry Brian N	Director	AGRANT◆	15,400	—	—	—	Open the original filing on SEC.gov
Jan 12	Cherry Brian N	Director	AGRANT◆	23,000	—	—	—	Open the original filing on SEC.gov
Jan 6	Patterson Leone D	EVP, Chief Bus & Fin…	AGRANT	459	$10.55	$4.8K	—	Open the original filing on SEC.gov
Jan 5	Smith Jeffrey T L	EVP & Chief Medical…	MEXER◆	20,000	—	—	—	Open the original filing on SEC.gov
Jan 5	Smith Jeffrey T L	EVP & Chief Medical…	SSELL	10,538	$25.10	$264.5K	-36.5%	Open the original filing on SEC.gov
Jan 5	Smith Jeffrey T L	EVP & Chief Medical…	MEXER	20,000	—	—	+225.0%	Open the original filing on SEC.gov
Jan 5	Moore Paul Andrew	Chief Scientific Officer	MEXER◆	20,000	—	—	—	Open the original filing on SEC.gov
Jan 5	Moore Paul Andrew	Chief Scientific Officer	MEXER◆	17,168	—	—	—	Open the original filing on SEC.gov
Jan 5	Moore Paul Andrew	Chief Scientific Officer	SSELL	10,821	$25.10	$271.6K	-21.1%	Open the original filing on SEC.gov
Jan 5	Moore Paul Andrew	Chief Scientific Officer	MEXER	20,000	—	—	+64.1%	Open the original filing on SEC.gov
Jan 5	Moore Paul Andrew	Chief Scientific Officer	SSELL	9,289	$25.10	$233.1K	-22.9%	Open the original filing on SEC.gov
Jan 5	Moore Paul Andrew	Chief Scientific Officer	MEXER	17,168	—	—	+73.6%	Open the original filing on SEC.gov
Jan 5	Galbraith Kenneth	Chair & CEO	MEXER◆	66,666	—	—	—	Open the original filing on SEC.gov
Jan 5	Galbraith Kenneth	Chair & CEO	MEXER◆	47,668	—	—	—	Open the original filing on SEC.gov
Jan 5	Galbraith Kenneth	Chair & CEO	SSELL	31,686	$25.10	$795.2K	-14.1%	Open the original filing on SEC.gov
Jan 5	Galbraith Kenneth	Chair & CEO	MEXER	66,666	—	—	+42.1%	Open the original filing on SEC.gov
Jan 5	Galbraith Kenneth	Chair & CEO	SSELL	22,657	$25.10	$568.6K	-12.5%	Open the original filing on SEC.gov
Jan 5	Galbraith Kenneth	Chair & CEO	MEXER	47,668	—	—	+35.8%	Open the original filing on SEC.gov
Dec 22, 2025	Galbraith Kenneth	Chair & CEO	MEXER◆	100,000	—	—	—	Open the original filing on SEC.gov
Dec 22, 2025	Galbraith Kenneth	Chair & CEO	SSELL	47,528	$27.02	$1.3M	-26.3%	Open the original filing on SEC.gov
Dec 22, 2025	Galbraith Kenneth	Chair & CEO	MEXER	100,000	—	—	+123.8%	Open the original filing on SEC.gov
Aug 12, 2025	Ciongoli Gregory Austin	Director	AGRANT	415,000	$12.02	$5M	+564.6%	Open the original filing on SEC.gov
Aug 11, 2025	Landry Robert E	Director	AGRANT◆	62,000	—	—	—	Open the original filing on SEC.gov
Aug 11, 2025	Ciongoli Gregory Austin	Director	AGRANT◆	62,000	—	—	—	Open the original filing on SEC.gov
Jun 26, 2025	EcoR1 Capital, LLC	Director, 10% Owner	XXITM◆	5.1M	—	—	—	Open the original filing on SEC.gov
Jun 26, 2025	EcoR1 Capital, LLC	Director, 10% Owner	FTAX	41	$12.71	$521	0.0%	Open the original filing on SEC.gov
Jun 26, 2025	EcoR1 Capital, LLC	Director, 10% Owner	XXITM	5.1M	$0.0001	$509	+28.4%	Open the original filing on SEC.gov
May 19, 2025	EcoR1 Capital, LLC	Director, 10% Owner	PBUY	5,919	$11.78	$69.7K	+<0.1%	Open the original filing on SEC.gov
May 15, 2025	EcoR1 Capital, LLC	Director, 10% Owner	PBUY	49,502	$11.43	$565.8K	+0.3%	Open the original filing on SEC.gov
Apr 17, 2025	EcoR1 Capital, LLC	Director, 10% Owner	PBUY	54,760	$11.52	$630.8K	+0.3%	Open the original filing on SEC.gov
Apr 16, 2025	EcoR1 Capital, LLC	Director, 10% Owner	PBUY	73,953	$11.16	$825.6K	+0.4%	Open the original filing on SEC.gov

AGRANT$20.9K

Hollywood Mark · EVP & Chief…Jul 6

939 sh @ $22.22 · +0.7% own

AGRANT◆—

Schneider Paul R · EVP, General…May 13

119,000 sh

AGRANT◆—

Schneider Paul R · EVP, General…May 13

178,000 sh

AGRANT◆—

Schayowitz Adam · See RemarksApr 9

76,000 sh

AGRANT◆—

Schayowitz Adam · See RemarksApr 9

47,000 sh

AGRANT◆—

Schayowitz Adam · See RemarksApr 9

70,000 sh

AGRANT◆—

Platshon Scott · EVP, Chief Busines…Apr 9

76,000 sh

AGRANT◆—

Platshon Scott · EVP, Chief Busines…Apr 9

47,000 sh

AGRANT◆—

Platshon Scott · EVP, Chief Busines…Apr 9

70,000 sh

AGRANT◆—

Stafford Kristin · EVP, Chief Financi…Apr 6

50,000 sh

AGRANT◆—

Stafford Kristin · EVP, Chief Financi…Apr 6

119,000 sh

AGRANT◆—

Stafford Kristin · EVP, Chief Financi…Apr 6

178,000 sh

MEXER◆—

Smith Jeffrey T L · EVP & Chief…Jan 12

17,666 sh

SSELL$211.1K

Smith Jeffrey T L · EVP & Chief…Jan 12

9,310 sh @ $22.67 · -25.9% own

MEXER—

Smith Jeffrey T L · EVP & Chief…Jan 12

17,666 sh · +96.3% own

AGRANT◆—

Neu Kelvin · DirectorJan 12

7,700 sh

AGRANT◆—

Neu Kelvin · DirectorJan 12

11,500 sh

AGRANT◆—

Moore Paul Andrew · Chief Scientific…Jan 12

66,000 sh

AGRANT◆—

Moore Paul Andrew · Chief Scientific…Jan 12

47,000 sh

AGRANT◆—

Moore Paul Andrew · Chief Scientific…Jan 12

70,000 sh

MEXER◆—

Moore Paul Andrew · Chief Scientific…Jan 12

17,666 sh

SSELL$216.8K

Moore Paul Andrew · Chief Scientific…Jan 12

9,560 sh @ $22.67 · -16.5% own

MEXER—

Moore Paul Andrew · Chief Scientific…Jan 12

17,666 sh · +43.7% own

AGRANT◆—

Mahony Susan · DirectorJan 12

7,700 sh

AGRANT◆—

Mahony Susan · DirectorJan 12

11,500 sh

AGRANT◆—

Landry Robert E · DirectorJan 12

7,700 sh

AGRANT◆—

Landry Robert E · DirectorJan 12

11,500 sh

AGRANT◆—

Galbraith Kenneth · Chair & CEOJan 12

222,000 sh

AGRANT◆—

Galbraith Kenneth · Chair & CEOJan 12

144,000 sh

AGRANT◆—

Galbraith Kenneth · Chair & CEOJan 12

216,000 sh

MEXER◆—

Galbraith Kenneth · Chair & CEOJan 12

64,000 sh

SSELL$689.8K

Galbraith Kenneth · Chair & CEOJan 12

30,424 sh @ $22.67 · -11.8% own

MEXER—

Galbraith Kenneth · Chair & CEOJan 12

64,000 sh · +33.1% own

AGRANT◆—

Ciongoli Gregory Austin · DirectorJan 12

7,700 sh

AGRANT◆—

Ciongoli Gregory Austin · DirectorJan 12

11,500 sh

AGRANT◆—

Cesano Alessandra · DirectorJan 12

7,700 sh

AGRANT◆—

Cesano Alessandra · DirectorJan 12

11,500 sh

AGRANT◆—

Campoy Carlos · DirectorJan 12

7,700 sh

AGRANT◆—

Campoy Carlos · DirectorJan 12

11,500 sh

AGRANT◆—

Hollywood Mark · EVP & Chief…Jan 12

66,000 sh

AGRANT◆—

Hollywood Mark · EVP & Chief…Jan 12

47,000 sh

AGRANT◆—

Hollywood Mark · EVP & Chief…Jan 12

70,000 sh

MEXER◆—

Hollywood Mark · EVP & Chief…Jan 12

17,666 sh

SSELL$138.8K

Hollywood Mark · EVP & Chief…Jan 12

6,120 sh @ $22.67 · -4.4% own

MEXER—

Hollywood Mark · EVP & Chief…Jan 12

17,666 sh · +14.6% own

AGRANT◆—

Cherry Brian N · DirectorJan 12

15,400 sh

AGRANT◆—

Cherry Brian N · DirectorJan 12

23,000 sh

AGRANT$4.8K

Patterson Leone D · EVP, Chief Bus &…Jan 6

459 sh @ $10.55

MEXER◆—

Smith Jeffrey T L · EVP & Chief…Jan 5

20,000 sh

SSELL$264.5K

Smith Jeffrey T L · EVP & Chief…Jan 5

10,538 sh @ $25.10 · -36.5% own

MEXER—

Smith Jeffrey T L · EVP & Chief…Jan 5

20,000 sh · +225.0% own

MEXER◆—

Moore Paul Andrew · Chief Scientific…Jan 5

20,000 sh

MEXER◆—

Moore Paul Andrew · Chief Scientific…Jan 5

17,168 sh

SSELL$271.6K

Moore Paul Andrew · Chief Scientific…Jan 5

10,821 sh @ $25.10 · -21.1% own

MEXER—

Moore Paul Andrew · Chief Scientific…Jan 5

20,000 sh · +64.1% own

SSELL$233.1K

Moore Paul Andrew · Chief Scientific…Jan 5

9,289 sh @ $25.10 · -22.9% own

MEXER—

Moore Paul Andrew · Chief Scientific…Jan 5

17,168 sh · +73.6% own

MEXER◆—

Galbraith Kenneth · Chair & CEOJan 5

66,666 sh

MEXER◆—

Galbraith Kenneth · Chair & CEOJan 5

47,668 sh

SSELL$795.2K

Galbraith Kenneth · Chair & CEOJan 5

31,686 sh @ $25.10 · -14.1% own

MEXER—

Galbraith Kenneth · Chair & CEOJan 5

66,666 sh · +42.1% own

SSELL$568.6K

Galbraith Kenneth · Chair & CEOJan 5

22,657 sh @ $25.10 · -12.5% own

MEXER—

Galbraith Kenneth · Chair & CEOJan 5

47,668 sh · +35.8% own

MEXER◆—

Galbraith Kenneth · Chair & CEODec 22, 2025

100,000 sh

SSELL$1.3M

Galbraith Kenneth · Chair & CEODec 22, 2025

47,528 sh @ $27.02 · -26.3% own

MEXER—

Galbraith Kenneth · Chair & CEODec 22, 2025

100,000 sh · +123.8% own

AGRANT$5M

Ciongoli Gregory Austin · DirectorAug 12, 2025

415,000 sh @ $12.02 · +564.6% own

AGRANT◆—

Landry Robert E · DirectorAug 11, 2025

62,000 sh

AGRANT◆—

Ciongoli Gregory Austin · DirectorAug 11, 2025

62,000 sh

XXITM◆—

EcoR1 Capital, LLC · Director, 10%…Jun 26, 2025

5.1M sh

FTAX$521

EcoR1 Capital, LLC · Director, 10%…Jun 26, 2025

41 sh @ $12.71 · 0.0% own

XXITM$509

EcoR1 Capital, LLC · Director, 10%…Jun 26, 2025

5.1M sh @ $0.0001 · +28.4% own

PBUY$69.7K

EcoR1 Capital, LLC · Director, 10%…May 19, 2025

5,919 sh @ $11.78 · +<0.1% own

PBUY$565.8K

EcoR1 Capital, LLC · Director, 10%…May 15, 2025

49,502 sh @ $11.43 · +0.3% own

PBUY$630.8K

EcoR1 Capital, LLC · Director, 10%…Apr 17, 2025

54,760 sh @ $11.52 · +0.3% own

PBUY$825.6K

EcoR1 Capital, LLC · Director, 10%…Apr 16, 2025

73,953 sh @ $11.16 · +0.4% own

Filing record

How quickly insiders here report their trades. Section 16 allows two business days from the transaction.

All 12 filings we hold were filed within the two-business-day deadline.

Counted in business days from the transaction date, or the deemed execution date where the filing reports one, excluding weekends and federal holidays. How this is measured · All late filings

Insiders at this company

Everyone who has filed a Form 4 for this issuer.

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