| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS◆ | 135,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS◆ | 110,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS◆ | 156,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS◆ | 156,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS◆ | 21,635 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS◆ | 96,051 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS◆ | 119,923 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS◆ | 49,968 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Ziolkowski Jennifer Lynn | Chief Financial Officer | DTOISS | 4,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Vitorovic Stefan | Director | DTOISS◆ | 12,155 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Vitorovic Stefan | Director | DTOISS◆ | 13,928 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Vitorovic Stefan | Director | DTOISS◆ | 18,068 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Vitorovic Stefan | Director | DTOISS | 5,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Thistle Mary | Director | DTOISS◆ | 12,155 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Thistle Mary | Director | DTOISS◆ | 24,309 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Thistle Mary | Director | DTOISS◆ | 13,928 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Thistle Mary | Director | DTOISS◆ | 18,068 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Thistle Mary | Director | DTOISS | 5,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS◆ | 485,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS◆ | 463,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS◆ | 370,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS◆ | 282,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS◆ | 43,271 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS◆ | 405,494 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS◆ | 210,629 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS◆ | 369,351 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Magovcevic-Liebisch… | President and CEO | DTOISS | 222,687 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Koenig Gerhard | Director | DTOISS◆ | 12,155 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Koenig Gerhard | Director | DTOISS◆ | 4,351 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Koenig Gerhard | Director | DTOISS◆ | 13,928 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Koenig Gerhard | Director | DTOISS◆ | 18,068 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Koenig Gerhard | Director | DTOISS◆ | 36,690 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Koenig Gerhard | Director | DTOISS◆ | 6,954 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Koenig Gerhard | Director | DTOISS◆ | 18,029 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Koenig Gerhard | Director | DTOISS | 5,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Kaufmann Petra | Chief Medical Officer | DTOISS◆ | 330,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Kaufmann Petra | Chief Medical Officer | DTOISS◆ | 144,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Gray David L. F. | Chief Science Officer | DTOISS◆ | 267,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Gray David L. F. | Chief Science Officer | DTOISS◆ | 125,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Gray David L. F. | Chief Science Officer | DTOISS◆ | 125,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Budd Haeberlein… | Director | DTOISS◆ | 30,694 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Budd Haeberlein… | Director | DTOISS◆ | 13,928 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Budd Haeberlein… | Director | DTOISS◆ | 18,068 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Budd Haeberlein… | Director | DTOISS | 12,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Budd Haeberlein… | Director | DTOISS | 5,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Bruhn Suzanne Louise | Director | DTOISS◆ | 6,235 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Bruhn Suzanne Louise | Director | DTOISS◆ | 24,310 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Bruhn Suzanne Louise | Director | DTOISS◆ | 13,928 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Bruhn Suzanne Louise | Director | DTOISS◆ | 33,875 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Bruhn Suzanne Louise | Director | DTOISS◆ | 18,068 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Bruhn Suzanne Louise | Director | DTOISS◆ | 24,073 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Bruhn Suzanne Louise | Director | DTOISS | 5,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS◆ | 48,393 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS◆ | 18,068 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS◆ | 34,612 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS◆ | 13,928 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS◆ | 9,713 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS◆ | 12,155 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS◆ | 7,577 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS | 1M | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS | 4.8M | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Booth Bruce | Director | DTOISS | 5,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS◆ | 6,432 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS◆ | 12,155 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS◆ | 5,017 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS◆ | 13,928 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS◆ | 18,068 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS◆ | 36,690 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS◆ | 24,984 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS◆ | 24,761 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Blanchard Cheryl R | Director | DTOISS | 5,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Atlas Venture Fund XII,… | 10% Owner | DTOISS | 1M | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 5, 2025 | Atlas Venture Fund XII,… | 10% Owner | DTOISS | 4.8M | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| May 22, 2025 | Vitorovic Stefan | Director | AGRANT | 5,000 | — | — | — | ↗Open the original filing on SEC.gov |
| May 22, 2025 | Thistle Mary | Director | AGRANT | 5,000 | — | — | — | ↗Open the original filing on SEC.gov |
| May 22, 2025 | Koenig Gerhard | Director | AGRANT | 5,000 | — | — | — | ↗Open the original filing on SEC.gov |
| May 22, 2025 | Budd Haeberlein… | Director | AGRANT | 5,000 | — | — | +41.7% | ↗Open the original filing on SEC.gov |
| May 22, 2025 | Bruhn Suzanne Louise | Director | AGRANT | 5,000 | — | — | — | ↗Open the original filing on SEC.gov |
| May 22, 2025 | Booth Bruce | Director | AGRANT | 5,000 | — | — | — | ↗Open the original filing on SEC.gov |
| May 22, 2025 | Blanchard Cheryl R | Director | AGRANT | 5,000 | — | — | — | ↗Open the original filing on SEC.gov |