| Feb 27 | McCarthy Teresa | Chief Human Resources… | DTOISS◆ | 50,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | McCarthy Teresa | Chief Human Resources… | DTOISS◆ | 78,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | McCarthy Teresa | Chief Human Resources… | DTOISS◆ | 54,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | McCarthy Teresa | Chief Human Resources… | DTOISS◆ | 108,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | McCarthy Teresa | Chief Human Resources… | DTOISS◆ | 57,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | McCarthy Teresa | Chief Human Resources… | DTOISS◆ | 65,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | McCarthy Teresa | Chief Human Resources… | DTOISS◆ | 106,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | McCarthy Teresa | Chief Human Resources… | DTOISS | 165,296 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Thompson Tamar | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Thompson Tamar | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Thompson Tamar | Director | DTOISS◆ | 13,489 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Thompson Tamar | Director | DTOISS◆ | 10,034 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Thompson Tamar | Director | DTOISS | 6,692 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | MacLean Michael F | Chief Financial Officer | DTOISS◆ | 50,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | MacLean Michael F | Chief Financial Officer | DTOISS◆ | 106,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | MacLean Michael F | Chief Financial Officer | DTOISS◆ | 60,125 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | MacLean Michael F | Chief Financial Officer | DTOISS◆ | 148,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | MacLean Michael F | Chief Financial Officer | DTOISS◆ | 131,250 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | MacLean Michael F | Chief Financial Officer | DTOISS◆ | 92,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | MacLean Michael F | Chief Financial Officer | DTOISS | 133,977 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Skerjanec Simona | Director | DTOISS◆ | 42,308 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Skerjanec Simona | Director | DTOISS◆ | 10,034 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Skerjanec Simona | Director | DTOISS | 6,692 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Hughes Steven George | Chief Medical Officer | DTOISS◆ | 50,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Hughes Steven George | Chief Medical Officer | DTOISS◆ | 68,458 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Hughes Steven George | Chief Medical Officer | DTOISS◆ | 49,333 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Hughes Steven George | Chief Medical Officer | DTOISS◆ | 74,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Hughes Steven George | Chief Medical Officer | DTOISS◆ | 73,342 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Hughes Steven George | Chief Medical Officer | DTOISS | 115,857 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Boyce Sarah | President and CEO | DTOISS◆ | 165,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boyce Sarah | President and CEO | DTOISS◆ | 300,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boyce Sarah | President and CEO | DTOISS◆ | 200,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boyce Sarah | President and CEO | DTOISS◆ | 400,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boyce Sarah | President and CEO | DTOISS◆ | 425,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boyce Sarah | President and CEO | DTOISS◆ | 300,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boyce Sarah | President and CEO | DTOISS◆ | 386,015 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boyce Sarah | President and CEO | DTOISS | 474,861 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Moriarty John B | Chief Legal Officer | DTOISS◆ | 160,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Moriarty John B | Chief Legal Officer | DTOISS◆ | 50,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Moriarty John B | Chief Legal Officer | DTOISS | 92,054 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Flanagan W. Michael | Chief Scientific Officer | DTOISS◆ | 50,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Flanagan W. Michael | Chief Scientific Officer | DTOISS◆ | 88,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Flanagan W. Michael | Chief Scientific Officer | DTOISS◆ | 72,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Flanagan W. Michael | Chief Scientific Officer | DTOISS◆ | 96,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Flanagan W. Michael | Chief Scientific Officer | DTOISS◆ | 66,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Flanagan W. Michael | Chief Scientific Officer | DTOISS◆ | 25,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Flanagan W. Michael | Chief Scientific Officer | DTOISS | 150,365 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Wilson Troy Edward | Director | DTOISS◆ | 15,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Wilson Troy Edward | Director | DTOISS◆ | 13,489 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Wilson Troy Edward | Director | DTOISS◆ | 10,034 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Wilson Troy Edward | Director | DTOISS | 13,711 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Wilson Troy Edward | Director | DTOISS | 65,091 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 50,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 16,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 13,520 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 42,480 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 27,584 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 13,352 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 9,244 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 13,829 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS◆ | 22,321 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Gallagher Kathleen P. | Chief Program Officer | DTOISS | 80,303 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Henig Noreen | Director | DTOISS◆ | 9,534 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Henig Noreen | Director | DTOISS◆ | 11,323 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Henig Noreen | Director | DTOISS◆ | 15,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Henig Noreen | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Henig Noreen | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Henig Noreen | Director | DTOISS◆ | 13,489 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Henig Noreen | Director | DTOISS◆ | 10,034 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Henig Noreen | Director | DTOISS | 6,692 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Kim Jean Jinsun | Director | DTOISS◆ | 30,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kim Jean Jinsun | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kim Jean Jinsun | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kim Jean Jinsun | Director | DTOISS◆ | 13,489 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kim Jean Jinsun | Director | DTOISS◆ | 10,034 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kim Jean Jinsun | Director | DTOISS | 6,692 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Levin Arthur A | Director | DTOISS◆ | 12,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Levin Arthur A | Director | DTOISS◆ | 115,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Levin Arthur A | Director | DTOISS◆ | 144,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Levin Arthur A | Director | DTOISS◆ | 13,489 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Levin Arthur A | Director | DTOISS◆ | 10,034 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Levin Arthur A | Director | DTOISS | 131,372 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Levin Arthur A | Director | DTOISS | 16,562 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Kaye Edward M. MD | Director | DTOISS◆ | 9,534 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kaye Edward M. MD | Director | DTOISS◆ | 11,323 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kaye Edward M. MD | Director | DTOISS◆ | 15,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kaye Edward M. MD | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kaye Edward M. MD | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kaye Edward M. MD | Director | DTOISS◆ | 13,489 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kaye Edward M. MD | Director | DTOISS◆ | 10,034 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Kaye Edward M. MD | Director | DTOISS | 6,692 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Boess Carsten | Director | DTOISS◆ | 20,858 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boess Carsten | Director | DTOISS◆ | 15,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boess Carsten | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boess Carsten | Director | DTOISS◆ | 22,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boess Carsten | Director | DTOISS◆ | 13,489 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boess Carsten | Director | DTOISS◆ | 10,034 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Boess Carsten | Director | DTOISS | 6,692 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Feb 27 | Mosbrooker Eric | Chief Commercial Officer | DTOISS◆ | 50,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Feb 27 | Mosbrooker Eric | Chief Commercial Officer | DTOISS◆ | 177,188 | — | — | — | ↗Open the original filing on SEC.gov |