| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 371,875 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 218,250 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 34,375 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 31,250 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 37,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 18,750 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 7,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 10,417 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 8,334 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | DTOISS◆ | 25,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Wong Brian Russell | President and CEO | UTENDR | 64,102 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Mar 3 | Young Rodney KB | Chief Financial Officer | DTOISS◆ | 69,271 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Young Rodney KB | Chief Financial Officer | DTOISS◆ | 80,250 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Young Rodney KB | Chief Financial Officer | DTOISS◆ | 11,251 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Young Rodney KB | Chief Financial Officer | DTOISS◆ | 8,501 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Young Rodney KB | Chief Financial Officer | DTOISS◆ | 8,125 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Young Rodney KB | Chief Financial Officer | DTOISS◆ | 7,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Young Rodney KB | Chief Financial Officer | DTOISS◆ | 17,501 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Young Rodney KB | Chief Financial Officer | UTENDR | 3,304 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Mar 3 | Lyons-Williams Lori | Director | DTOISS◆ | 32,229 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Lyons-Williams Lori | Director | DTOISS◆ | 4,561 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Lyons-Williams Lori | Director | DTOISS◆ | 1,618 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Lyons-Williams Lori | Director | DTOISS◆ | 1,063 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Lyons-Williams Lori | Director | DTOISS◆ | 2,813 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Lyons-Williams Lori | Director | UTENDR | 4,956 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 32,229 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 4,561 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 1,618 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 1,063 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 938 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 938 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 417 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 1,917 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 521 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 521 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | DTOISS◆ | 2,083 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Kozick Linda | Director | UTENDR | 4,956 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 32,229 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 4,561 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 1,618 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 1,063 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 402 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 938 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 938 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 799 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | DTOISS◆ | 824 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Giordano Michael F | Director | UTENDR | 4,956 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 32,229 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 7,650 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 4,561 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 1,072 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 1,618 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 560 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 1,063 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 484 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 938 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 478 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 938 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 498 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | DTOISS◆ | 2,813 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Gray Mary Ann | Director | UTENDR | 4,956 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Mar 3 | Dombkowski Ashley L. | Director | DTOISS◆ | 25,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Dombkowski Ashley L. | Director | UTENDR | 4,956 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 58,333 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 64,375 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 9,375 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 7,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 6,876 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 6,250 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 2,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 3,125 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 1,035 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | DTOISS◆ | 1,225 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Brockstedt Dirk G. | Chief Scientific Officer | UTENDR | 4,648 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Mar 3 | Braunstein Scott | Director | DTOISS◆ | 25,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Mar 3 | Braunstein Scott | Director | UTENDR | 4,956 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Jan 30 | Lyons-Williams Lori | Director | AGRANT | 4,956 | — | — | — | ↗Open the original filing on SEC.gov |
| Jan 30 | Kozick Linda | Director | AGRANT | 4,956 | — | — | — | ↗Open the original filing on SEC.gov |
| Jan 30 | Giordano Michael F | Director | AGRANT | 4,956 | — | — | — | ↗Open the original filing on SEC.gov |
| Jan 30 | Gray Mary Ann | Director | AGRANT | 4,956 | — | — | — | ↗Open the original filing on SEC.gov |
| Jan 30 | Dombkowski Ashley L. | Director | AGRANT | 4,956 | — | — | — | ↗Open the original filing on SEC.gov |
| Jan 30 | Braunstein Scott | Director | AGRANT | 4,956 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 21, 2025 | Braunstein Scott | Director | AGRANT◆ | 25,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 21, 2025 | Dombkowski Ashley L. | Director | AGRANT◆ | 25,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 20, 2025 | Wong Brian Russell | President and CEO | AGRANT◆ | 637,500 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 20, 2025 | Young Rodney KB | Chief Financial Officer | AGRANT◆ | 118,750 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 20, 2025 | Ho William | Chief Medical Officer | AGRANT◆ | 75,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 20, 2025 | Brockstedt Dirk G. | Chief Scientific Officer | AGRANT◆ | 100,000 | — | — | — | ↗Open the original filing on SEC.gov |
| May 29, 2025 | Lyons-Williams Lori | Director | AGRANT◆ | 257,832 | — | — | — | ↗Open the original filing on SEC.gov |
| May 29, 2025 | Kozick Linda | Director | AGRANT◆ | 257,832 | — | — | — | ↗Open the original filing on SEC.gov |
| May 29, 2025 | Giordano Michael F | Director | AGRANT◆ | 257,832 | — | — | — | ↗Open the original filing on SEC.gov |
| May 29, 2025 | Gray Mary Ann | Director | AGRANT◆ | 257,832 | — | — | — | ↗Open the original filing on SEC.gov |