PRME

Prime Medicine, Inc.

Insider trading activity for Prime Medicine, Inc., straight from SEC Form 4 filings. Net figures below count open-market buys and sales only — grants, option exercises and tax withholding are excluded because they are compensation, not decisions to trade.

Past 3 months

net buying

Bought(0 · 0 insiders): $0
Sold(0 · 0 insiders): $0

Past 6 months

net buying

Bought(0 · 0 insiders): $0
Sold(0 · 0 insiders): $0

Past 12 months

net buying

Bought(0 · 0 insiders): $0
Sold(0 · 0 insiders): $0

Transaction history

The 90 most recent Form 4 transactions.

Open in screener →

Insider transactions, newest first: date, security, transaction type, size and a link to the filing each row came from.
Date	Insider	Role	Type	Shares	Price	Value	Δ Own	Filing
Jun 5	Schenkein David P	Director	AGRANT◆	75,000	—	—	—	Open the original filing on SEC.gov
Jun 5	Nelsen Robert	Director, 10% Owner	AGRANT◆	75,000	—	—	—	Open the original filing on SEC.gov
Jun 5	Marrazzo Jeffrey D	Director	AGRANT◆	75,000	—	—	—	Open the original filing on SEC.gov
Jun 5	Kelly Michael Aaron	Director	AGRANT◆	75,000	—	—	—	Open the original filing on SEC.gov
Jun 5	Foster-Cheek Kaye I	Director	AGRANT◆	75,000	—	—	—	Open the original filing on SEC.gov
Jun 5	Chung Wendy	Director	AGRANT◆	75,000	—	—	—	Open the original filing on SEC.gov
Jun 5	Cahill Thomas	Director	AGRANT◆	75,000	—	—	—	Open the original filing on SEC.gov
Apr 16	Makhni Svetlana Ni	Chief Financial Officer	AGRANT◆	800,000	—	—	—	Open the original filing on SEC.gov
Feb 26	Reine Allan	Chief Executive Officer	AGRANT◆	1.3M	—	—	—	Open the original filing on SEC.gov
Feb 23	Lee Ann L.	Chief Technical Officer	AGRANT◆	375,000	—	—	—	Open the original filing on SEC.gov
Feb 23	Alenson Carman	See Remarks	AGRANT◆	140,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Nelsen Robert	Director, 10% Owner	PBUY	3M	$3.30	$10M	+94.7%	Open the original filing on SEC.gov
Aug 1, 2025	ARCH Venture Partners…	10% Owner	PBUY	3M	$3.30	$10M	+94.7%	Open the original filing on SEC.gov
Aug 1, 2025	ARCH Venture Partners…	10% Owner	PBUY	3M	$3.30	$10M	+94.7%	Open the original filing on SEC.gov
Aug 1, 2025	Schenkein David P	Director	AGRANT◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Schenkein David P	Director	DTOISS◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Schenkein David P	Director	AGRANT◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Schenkein David P	Director	DTOISS◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Reine Allan	Chief Executive Officer	AGRANT◆	850,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Reine Allan	Chief Executive Officer	DTOISS◆	850,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Nelsen Robert	Director, 10% Owner	AGRANT◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Nelsen Robert	Director, 10% Owner	DTOISS◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Nelsen Robert	Director, 10% Owner	AGRANT◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Nelsen Robert	Director, 10% Owner	DTOISS◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Marrazzo Jeffrey D	Director	AGRANT◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Marrazzo Jeffrey D	Director	DTOISS◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Marrazzo Jeffrey D	Director	AGRANT◆	250,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Marrazzo Jeffrey D	Director	DTOISS◆	250,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Marrazzo Jeffrey D	Director	AGRANT◆	92,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Marrazzo Jeffrey D	Director	DTOISS◆	92,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Lee Ann L.	Chief Technical Officer	AGRANT◆	180,995	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Lee Ann L.	Chief Technical Officer	DTOISS◆	180,995	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Lee Ann L.	Chief Technical Officer	AGRANT◆	180,995	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Lee Ann L.	Chief Technical Officer	DTOISS◆	180,995	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Kelly Michael Aaron	Director	AGRANT◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Kelly Michael Aaron	Director	DTOISS◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Kelly Michael Aaron	Director	AGRANT◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Kelly Michael Aaron	Director	DTOISS◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Kelly Michael Aaron	Director	AGRANT◆	9,006	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Kelly Michael Aaron	Director	DTOISS◆	9,006	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Kelly Michael Aaron	Director	AGRANT◆	13,510	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Kelly Michael Aaron	Director	DTOISS◆	13,510	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Foster-Cheek Kaye I	Director	AGRANT◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Foster-Cheek Kaye I	Director	DTOISS◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Foster-Cheek Kaye I	Director	AGRANT◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Foster-Cheek Kaye I	Director	DTOISS◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Foster-Cheek Kaye I	Director	AGRANT◆	9,006	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Foster-Cheek Kaye I	Director	DTOISS◆	9,006	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Foster-Cheek Kaye I	Director	AGRANT◆	13,510	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Foster-Cheek Kaye I	Director	DTOISS◆	13,510	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Chung Wendy	Director	AGRANT◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Chung Wendy	Director	DTOISS◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Chung Wendy	Director	AGRANT◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Chung Wendy	Director	DTOISS◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Chung Wendy	Director	AGRANT◆	9,006	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Chung Wendy	Director	DTOISS◆	9,006	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Chung Wendy	Director	AGRANT◆	13,510	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Chung Wendy	Director	DTOISS◆	13,510	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Cahill Thomas	Director	AGRANT◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Cahill Thomas	Director	DTOISS◆	45,000	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Cahill Thomas	Director	AGRANT◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Cahill Thomas	Director	DTOISS◆	39,062	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Gv 2021 Gp, L.l.c.	10% Owner	PBUY	1.5M	$3.30	$5M	+85.1%	Open the original filing on SEC.gov
Aug 1, 2025	Alenson Carman	See Remarks	AGRANT◆	90,498	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Alenson Carman	See Remarks	DTOISS◆	90,498	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Alenson Carman	See Remarks	AGRANT◆	6,254	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Alenson Carman	See Remarks	DTOISS◆	6,254	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Alenson Carman	See Remarks	AGRANT◆	90,498	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Alenson Carman	See Remarks	DTOISS◆	90,498	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Alenson Carman	See Remarks	AGRANT◆	16,083	—	—	—	Open the original filing on SEC.gov
Aug 1, 2025	Alenson Carman	See Remarks	DTOISS◆	16,083	—	—	—	Open the original filing on SEC.gov
Jun 30, 2025	Liu David R.	10% Owner	PBUY◷	21,000	$2.52	$52.8K	+0.1%	Open the original filing on SEC.gov
Jun 23, 2025	Liu David R.	10% Owner	PBUY◷	21,000	$2.16	$45.4K	+0.1%	Open the original filing on SEC.gov
Jun 16, 2025	Liu David R.	10% Owner	PBUY◷	21,000	$1.49	$31.2K	+0.1%	Open the original filing on SEC.gov
Jun 11, 2025	Liu David R.	10% Owner	PBUY◷	21,000	$1.60	$33.6K	+0.1%	Open the original filing on SEC.gov
Jun 4, 2025	Schenkein David P	Director	AGRANT◆	55,000	—	—	—	Open the original filing on SEC.gov
Jun 4, 2025	Nelsen Robert	Director, 10% Owner	AGRANT◆	55,000	—	—	—	Open the original filing on SEC.gov
Jun 4, 2025	Marrazzo Jeffrey D	Director	AGRANT◆	55,000	—	—	—	Open the original filing on SEC.gov
Jun 4, 2025	Kelly Michael Aaron	Director	AGRANT◆	55,000	—	—	—	Open the original filing on SEC.gov
Jun 4, 2025	Foster-Cheek Kaye I	Director	AGRANT◆	55,000	—	—	—	Open the original filing on SEC.gov
Jun 4, 2025	Chung Wendy	Director	AGRANT◆	55,000	—	—	—	Open the original filing on SEC.gov
Jun 4, 2025	Cahill Thomas	Director	AGRANT◆	55,000	—	—	—	Open the original filing on SEC.gov
May 21, 2025	Reine Allan	Chief Executive Officer	PBUY	125,000	$1.18	$147.2K	—	Open the original filing on SEC.gov
May 21, 2025	Lee Ann L.	Chief Technical Officer	PBUY	100,000	$1.13	$113K	—	Open the original filing on SEC.gov
May 20, 2025	Brudnick Richard	Chief Business Officer	PBUY	20,000	$1.19	$23.8K	—	Open the original filing on SEC.gov
May 19, 2025	Reine Allan	Chief Executive Officer	AGRANT◆	2M	—	—	—	Open the original filing on SEC.gov
May 19, 2025	Marrazzo Jeffrey D	Director	AGRANT◆	800,000	—	—	—	Open the original filing on SEC.gov
May 8, 2025	Reine Allan	Chief Financial Officer	AGRANT◆	75,000	—	—	—	Open the original filing on SEC.gov
May 8, 2025	Lee Ann L.	Chief Technical Officer	AGRANT◆	80,416	—	—	—	Open the original filing on SEC.gov
May 8, 2025	Gottesdiener Keith…	See Remarks	AGRANT◆	100,000	—	—	—	Open the original filing on SEC.gov

AGRANT◆—

Schenkein David P · DirectorJun 5

75,000 sh

AGRANT◆—

Nelsen Robert · Director, 10%…Jun 5

75,000 sh

AGRANT◆—

Marrazzo Jeffrey D · DirectorJun 5

75,000 sh

AGRANT◆—

Kelly Michael Aaron · DirectorJun 5

75,000 sh

AGRANT◆—

Foster-Cheek Kaye I · DirectorJun 5

75,000 sh

AGRANT◆—

Chung Wendy · DirectorJun 5

75,000 sh

AGRANT◆—

Cahill Thomas · DirectorJun 5

75,000 sh

AGRANT◆—

Makhni Svetlana Ni · Chief Financial…Apr 16

800,000 sh

AGRANT◆—

Reine Allan · Chief Executive…Feb 26

1.3M sh

AGRANT◆—

Lee Ann L. · Chief Technical…Feb 23

375,000 sh

AGRANT◆—

Alenson Carman · See RemarksFeb 23

140,000 sh

PBUY$10M

Nelsen Robert · Director, 10%…Aug 1, 2025

3M sh @ $3.30 · +94.7% own

PBUY$10M

ARCH Venture Partners… · 10% OwnerAug 1, 2025

3M sh @ $3.30 · +94.7% own

PBUY$10M

ARCH Venture Partners… · 10% OwnerAug 1, 2025

3M sh @ $3.30 · +94.7% own

AGRANT◆—

Schenkein David P · DirectorAug 1, 2025

45,000 sh

DTOISS◆—

Schenkein David P · DirectorAug 1, 2025

45,000 sh

AGRANT◆—

Schenkein David P · DirectorAug 1, 2025

39,062 sh

DTOISS◆—

Schenkein David P · DirectorAug 1, 2025

39,062 sh

AGRANT◆—

Reine Allan · Chief Executive…Aug 1, 2025

850,000 sh

DTOISS◆—

Reine Allan · Chief Executive…Aug 1, 2025

850,000 sh

AGRANT◆—

Nelsen Robert · Director, 10%…Aug 1, 2025

45,000 sh

DTOISS◆—

Nelsen Robert · Director, 10%…Aug 1, 2025

45,000 sh

AGRANT◆—

Nelsen Robert · Director, 10%…Aug 1, 2025

39,062 sh

DTOISS◆—

Nelsen Robert · Director, 10%…Aug 1, 2025

39,062 sh

AGRANT◆—

Marrazzo Jeffrey D · DirectorAug 1, 2025

45,000 sh

DTOISS◆—

Marrazzo Jeffrey D · DirectorAug 1, 2025

45,000 sh

AGRANT◆—

Marrazzo Jeffrey D · DirectorAug 1, 2025

250,000 sh

DTOISS◆—

Marrazzo Jeffrey D · DirectorAug 1, 2025

250,000 sh

AGRANT◆—

Marrazzo Jeffrey D · DirectorAug 1, 2025

92,000 sh

DTOISS◆—

Marrazzo Jeffrey D · DirectorAug 1, 2025

92,000 sh

AGRANT◆—

Lee Ann L. · Chief Technical…Aug 1, 2025

180,995 sh

DTOISS◆—

Lee Ann L. · Chief Technical…Aug 1, 2025

180,995 sh

AGRANT◆—

Lee Ann L. · Chief Technical…Aug 1, 2025

180,995 sh

DTOISS◆—

Lee Ann L. · Chief Technical…Aug 1, 2025

180,995 sh

AGRANT◆—

Kelly Michael Aaron · DirectorAug 1, 2025

45,000 sh

DTOISS◆—

Kelly Michael Aaron · DirectorAug 1, 2025

45,000 sh

AGRANT◆—

Kelly Michael Aaron · DirectorAug 1, 2025

39,062 sh

DTOISS◆—

Kelly Michael Aaron · DirectorAug 1, 2025

39,062 sh

AGRANT◆—

Kelly Michael Aaron · DirectorAug 1, 2025

9,006 sh

DTOISS◆—

Kelly Michael Aaron · DirectorAug 1, 2025

9,006 sh

AGRANT◆—

Kelly Michael Aaron · DirectorAug 1, 2025

13,510 sh

DTOISS◆—

Kelly Michael Aaron · DirectorAug 1, 2025

13,510 sh

AGRANT◆—

Foster-Cheek Kaye I · DirectorAug 1, 2025

45,000 sh

DTOISS◆—

Foster-Cheek Kaye I · DirectorAug 1, 2025

45,000 sh

AGRANT◆—

Foster-Cheek Kaye I · DirectorAug 1, 2025

39,062 sh

DTOISS◆—

Foster-Cheek Kaye I · DirectorAug 1, 2025

39,062 sh

AGRANT◆—

Foster-Cheek Kaye I · DirectorAug 1, 2025

9,006 sh

DTOISS◆—

Foster-Cheek Kaye I · DirectorAug 1, 2025

9,006 sh

AGRANT◆—

Foster-Cheek Kaye I · DirectorAug 1, 2025

13,510 sh

DTOISS◆—

Foster-Cheek Kaye I · DirectorAug 1, 2025

13,510 sh

AGRANT◆—

Chung Wendy · DirectorAug 1, 2025

45,000 sh

DTOISS◆—

Chung Wendy · DirectorAug 1, 2025

45,000 sh

AGRANT◆—

Chung Wendy · DirectorAug 1, 2025

39,062 sh

DTOISS◆—

Chung Wendy · DirectorAug 1, 2025

39,062 sh

AGRANT◆—

Chung Wendy · DirectorAug 1, 2025

9,006 sh

DTOISS◆—

Chung Wendy · DirectorAug 1, 2025

9,006 sh

AGRANT◆—

Chung Wendy · DirectorAug 1, 2025

13,510 sh

DTOISS◆—

Chung Wendy · DirectorAug 1, 2025

13,510 sh

AGRANT◆—

Cahill Thomas · DirectorAug 1, 2025

45,000 sh

DTOISS◆—

Cahill Thomas · DirectorAug 1, 2025

45,000 sh

AGRANT◆—

Cahill Thomas · DirectorAug 1, 2025

39,062 sh

DTOISS◆—

Cahill Thomas · DirectorAug 1, 2025

39,062 sh

PBUY$5M

Gv 2021 Gp, L.l.c. · 10% OwnerAug 1, 2025

1.5M sh @ $3.30 · +85.1% own

AGRANT◆—

Alenson Carman · See RemarksAug 1, 2025

90,498 sh

DTOISS◆—

Alenson Carman · See RemarksAug 1, 2025

90,498 sh

AGRANT◆—

Alenson Carman · See RemarksAug 1, 2025

6,254 sh

DTOISS◆—

Alenson Carman · See RemarksAug 1, 2025

6,254 sh

AGRANT◆—

Alenson Carman · See RemarksAug 1, 2025

90,498 sh

DTOISS◆—

Alenson Carman · See RemarksAug 1, 2025

90,498 sh

AGRANT◆—

Alenson Carman · See RemarksAug 1, 2025

16,083 sh

DTOISS◆—

Alenson Carman · See RemarksAug 1, 2025

16,083 sh

PBUY◷$52.8K

Liu David R. · 10% OwnerJun 30, 2025

21,000 sh @ $2.52 · +0.1% own

PBUY◷$45.4K

Liu David R. · 10% OwnerJun 23, 2025

21,000 sh @ $2.16 · +0.1% own

PBUY◷$31.2K

Liu David R. · 10% OwnerJun 16, 2025

21,000 sh @ $1.49 · +0.1% own

PBUY◷$33.6K

Liu David R. · 10% OwnerJun 11, 2025

21,000 sh @ $1.60 · +0.1% own

AGRANT◆—

Schenkein David P · DirectorJun 4, 2025

55,000 sh

AGRANT◆—

Nelsen Robert · Director, 10%…Jun 4, 2025

55,000 sh

AGRANT◆—

Marrazzo Jeffrey D · DirectorJun 4, 2025

55,000 sh

AGRANT◆—

Kelly Michael Aaron · DirectorJun 4, 2025

55,000 sh

AGRANT◆—

Foster-Cheek Kaye I · DirectorJun 4, 2025

55,000 sh

AGRANT◆—

Chung Wendy · DirectorJun 4, 2025

55,000 sh

AGRANT◆—

Cahill Thomas · DirectorJun 4, 2025

55,000 sh

PBUY$147.2K

Reine Allan · Chief Executive…May 21, 2025

125,000 sh @ $1.18

PBUY$113K

Lee Ann L. · Chief Technical…May 21, 2025

100,000 sh @ $1.13

PBUY$23.8K

Brudnick Richard · Chief Business…May 20, 2025

20,000 sh @ $1.19

AGRANT◆—

Reine Allan · Chief Executive…May 19, 2025

2M sh

AGRANT◆—

Marrazzo Jeffrey D · DirectorMay 19, 2025

800,000 sh

AGRANT◆—

Reine Allan · Chief Financial…May 8, 2025

75,000 sh

AGRANT◆—

Lee Ann L. · Chief Technical…May 8, 2025

80,416 sh

AGRANT◆—

Gottesdiener Keith… · See RemarksMay 8, 2025

100,000 sh

Filing record

How quickly insiders here report their trades. Section 16 allows two business days from the transaction.

All 37 filings we hold were filed within the two-business-day deadline.

Counted in business days from the transaction date, or the deemed execution date where the filing reports one, excluding weekends and federal holidays. How this is measured · All late filings

Insiders at this company

Everyone who has filed a Form 4 for this issuer.

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