PRAX

Praxis Precision Medicines, Inc.

Insider trading activity for Praxis Precision Medicines, Inc., straight from SEC Form 4 filings. Net figures below count open-market buys and sales only — grants, option exercises and tax withholding are excluded because they are compensation, not decisions to trade.

Past 3 months

net buying

Bought(0 · 0 insiders): $0
Sold(0 · 0 insiders): $0

Past 6 months

-$3.6M

net selling

Bought(0 · 0 insiders): $0
Sold(12 · 1 insiders): $3.6M

Past 12 months

-$44.3M

net selling

Bought(0 · 0 insiders): $0
Sold(28 · 4 insiders): $44.3M

Transaction history

The 100 most recent Form 4 transactions.

Open in screener →

Insider transactions, newest first: date, security, transaction type, size and a link to the filing each row came from.
Date	Insider	Role	Type	Shares	Price	Value	Δ Own	Filing
Jul 8	Souza Marcio	Chief Executive Officer	GGIFT	2,600	—	—	-100.0%	Open the original filing on SEC.gov
Jul 8	Souza Marcio	Chief Executive Officer	GGIFT	20,521	—	—	-26.7%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	MEXER◷◆	3,034	—	—	—	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	MEXER◷◆	8,566	—	—	—	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	837	$315.71	$264.2K	-26.4%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	1,279	$314.90	$402.8K	-28.7%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	504	$313.66	$158.1K	-10.2%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	1,004	$312.83	$314.1K	-16.8%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	2,854	$311.91	$890.2K	-32.4%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	1,750	$310.89	$544.1K	-16.6%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	999	$309.38	$309.1K	-8.6%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	1,240	$308.24	$382.2K	-9.7%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	683	$306.77	$209.5K	-5.1%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	320	$305.31	$97.7K	-2.3%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	120	$303.13	$36.4K	-0.9%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	SSELL◷	10	$301.44	$3K	<0.1%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	MEXER◷	3,034	$147.30	$446.9K	+27.8%	Open the original filing on SEC.gov
Jun 24	DeSimone Jill	Director	MEXER◷	8,566	$44.25	$379K	+366.5%	Open the original filing on SEC.gov
Jun 10	Young William D	Director	AGRANT◆	648	—	—	—	Open the original filing on SEC.gov
Jun 10	Young William D	Director	AGRANT	1,371	—	—	+72.2%	Open the original filing on SEC.gov
Jun 10	Norden Gregory	Director	AGRANT◆	648	—	—	—	Open the original filing on SEC.gov
Jun 10	Norden Gregory	Director	AGRANT	1,371	—	—	+729.3%	Open the original filing on SEC.gov
Jun 10	Mitchell Dean J	Director	AGRANT◆	648	—	—	—	Open the original filing on SEC.gov
Jun 10	Mitchell Dean J	Director	AGRANT	1,371	—	—	+8.0%	Open the original filing on SEC.gov
Jun 10	Kindler Jeffrey B	Director	AGRANT◆	648	—	—	—	Open the original filing on SEC.gov
Jun 10	Kindler Jeffrey B	Director	AGRANT	1,371	—	—	+117.6%	Open the original filing on SEC.gov
Jun 10	DeSimone Jill	Director	AGRANT◆	648	—	—	—	Open the original filing on SEC.gov
Jun 10	DeSimone Jill	Director	AGRANT	1,371	—	—	+141.9%	Open the original filing on SEC.gov
Jun 10	Cudkowicz Merit Ester	Director	AGRANT◆	648	—	—	—	Open the original filing on SEC.gov
Jun 10	Cudkowicz Merit Ester	Director	AGRANT	1,371	—	—	—	Open the original filing on SEC.gov
Jun 10	Chodakewitz Jeffrey	Director	AGRANT◆	648	—	—	—	Open the original filing on SEC.gov
Jun 10	Chodakewitz Jeffrey	Director	AGRANT	1,371	—	—	—	Open the original filing on SEC.gov
Jun 10	Arbuckle Stuart A	Director	AGRANT◆	648	—	—	—	Open the original filing on SEC.gov
Jun 10	Arbuckle Stuart A	Director	AGRANT	1,371	—	—	+117.6%	Open the original filing on SEC.gov
May 14	Sniecinski Megan	Chief Operating Officer	AGRANT	89	$167.94	$14.9K	+0.3%	Open the original filing on SEC.gov
May 14	Souza Marcio	Chief Executive Officer	AGRANT	126	$167.94	$21.2K	+0.2%	Open the original filing on SEC.gov
May 14	Nemiroff Alex	General Counsel and…	AGRANT	78	$167.94	$13.1K	+0.3%	Open the original filing on SEC.gov
May 14	Mastrocola Lauren	Principal Accounting…	AGRANT	127	$167.94	$21.3K	+0.9%	Open the original filing on SEC.gov
May 14	Kelly Timothy Edwin	Chief Financial Officer	AGRANT	121	$167.94	$20.3K	+0.4%	Open the original filing on SEC.gov
Feb 6	Kindler Jeffrey B	Director	AGRANT◆	224	—	—	—	Open the original filing on SEC.gov
Feb 6	Kindler Jeffrey B	Director	AGRANT	478	—	—	+69.5%	Open the original filing on SEC.gov
Feb 6	Kindler Jeffrey B	Director	AGRANT	688	—	—	—	Open the original filing on SEC.gov
Feb 6	Arbuckle Stuart A	Director	AGRANT◆	224	—	—	—	Open the original filing on SEC.gov
Feb 6	Arbuckle Stuart A	Director	AGRANT	478	—	—	+69.5%	Open the original filing on SEC.gov
Feb 6	Arbuckle Stuart A	Director	AGRANT	688	—	—	—	Open the original filing on SEC.gov
Jan 12	Sniecinski Megan	Chief Operating Officer	FTAX	885	$275.74	$244K	-3.0%	Open the original filing on SEC.gov
Jan 12	Nemiroff Alex	General Counsel and…	FTAX	768	$275.74	$211.8K	-2.9%	Open the original filing on SEC.gov
Jan 12	Mastrocola Lauren	Principal Accounting…	FTAX	344	$275.74	$94.9K	-2.5%	Open the original filing on SEC.gov
Jan 12	Kelly Timothy Edwin	Chief Financial Officer	FTAX	943	$275.74	$260K	-2.9%	Open the original filing on SEC.gov
Jan 10	Sniecinski Megan	Chief Operating Officer	FTAX	1,087	$288.45	$313.5K	-3.6%	Open the original filing on SEC.gov
Jan 10	Souza Marcio	Chief Executive Officer	FTAX	4,252	$288.45	$1.2M	-5.2%	Open the original filing on SEC.gov
Jan 10	Nemiroff Alex	General Counsel and…	FTAX	917	$288.45	$264.5K	-3.3%	Open the original filing on SEC.gov
Jan 10	Mastrocola Lauren	Principal Accounting…	FTAX	367	$288.45	$105.9K	-2.6%	Open the original filing on SEC.gov
Jan 10	Kelly Timothy Edwin	Chief Financial Officer	FTAX	1,335	$288.45	$385.1K	-4.0%	Open the original filing on SEC.gov
Jan 8	Sniecinski Megan	Chief Operating Officer	AGRANT◆	7,700	—	—	—	Open the original filing on SEC.gov
Jan 8	Sniecinski Megan	Chief Operating Officer	AGRANT	9,625	—	—	+46.1%	Open the original filing on SEC.gov
Jan 8	Souza Marcio	Chief Executive Officer	AGRANT◆	22,110	—	—	—	Open the original filing on SEC.gov
Jan 8	Souza Marcio	Chief Executive Officer	AGRANT	27,640	—	—	+51.7%	Open the original filing on SEC.gov
Jan 8	Nemiroff Alex	General Counsel and…	AGRANT◆	5,500	—	—	—	Open the original filing on SEC.gov
Jan 8	Nemiroff Alex	General Counsel and…	AGRANT	6,875	—	—	+33.1%	Open the original filing on SEC.gov
Jan 8	Mastrocola Lauren	Principal Accounting…	AGRANT◆	7,500	—	—	—	Open the original filing on SEC.gov
Jan 8	Mastrocola Lauren	Principal Accounting…	AGRANT	3,750	—	—	+36.0%	Open the original filing on SEC.gov
Jan 8	Kelly Timothy Edwin	Chief Financial Officer	AGRANT◆	7,040	—	—	—	Open the original filing on SEC.gov
Jan 8	Kelly Timothy Edwin	Chief Financial Officer	AGRANT	8,800	—	—	+35.9%	Open the original filing on SEC.gov
Jan 7	Souza Marcio	Chief Executive Officer	FTAX	405	$292.63	$118.5K	-0.8%	Open the original filing on SEC.gov
Jan 7	Nemiroff Alex	General Counsel and…	FTAX	89	$292.63	$26K	-0.4%	Open the original filing on SEC.gov
Jan 7	Mastrocola Lauren	Principal Accounting…	FTAX	35	$292.63	$10.2K	-0.3%	Open the original filing on SEC.gov
Jan 7	Kelly Timothy Edwin	Chief Financial Officer	FTAX	139	$292.63	$40.7K	-0.6%	Open the original filing on SEC.gov
Dec 30, 2025	Souza Marcio	Chief Executive Officer	GGIFT	400	—	—	-13.3%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER◆	9,100	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER◆	5,652	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER◆	2,434	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER◆	6,230	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER◆	1,714	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	SSELL	9,100	$194.30	$1.8M	-30.4%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	SSELL	977	$193.23	$188.8K	-3.2%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	SSELL	13,339	$192.53	$2.6M	-30.1%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	SSELL	1,714	$190.86	$327.1K	-3.7%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER	9,100	$56.94	$518.2K	+24.7%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER	5,652	$44.40	$250.9K	+18.1%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER	2,434	$44.40	$108.1K	+8.5%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER	6,230	$133.65	$832.6K	+27.6%	Open the original filing on SEC.gov
Nov 20, 2025	Nemiroff Alex	General Counsel and…	MEXER	1,714	$83.85	$143.7K	+8.2%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER◆	5,250	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER◆	2,351	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER◆	207	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER◆	2,680	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER◆	1,557	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER◆	508	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER◆	1,047	—	—	—	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	SSELL	2,145	$192.71	$413.4K	-17.0%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	SSELL	11,455	$191.96	$2.2M	-47.6%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER	5,250	$56.94	$298.9K	+27.9%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER	2,351	$44.40	$104.4K	+14.3%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER	207	$44.40	$9.2K	+1.3%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER	2,680	$43.37	$116.2K	+19.8%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER	1,557	$133.65	$208.1K	+13.0%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER	508	$83.85	$42.6K	+4.4%	Open the original filing on SEC.gov
Nov 20, 2025	Mastrocola Lauren	Principal Accounting…	MEXER	1,047	$49.50	$51.8K	+10.0%	Open the original filing on SEC.gov
Nov 14, 2025	Kelly Timothy Edwin	Chief Financial Officer	AGRANT	384	$31.62	$12.1K	+1.6%	Open the original filing on SEC.gov

GGIFT—

Souza Marcio · Chief Executive…Jul 8

2,600 sh · -100.0% own

GGIFT—

Souza Marcio · Chief Executive…Jul 8

20,521 sh · -26.7% own

MEXER◷◆—

DeSimone Jill · DirectorJun 24

3,034 sh

MEXER◷◆—

DeSimone Jill · DirectorJun 24

8,566 sh

SSELL◷$264.2K

DeSimone Jill · DirectorJun 24

837 sh @ $315.71 · -26.4% own

SSELL◷$402.8K

DeSimone Jill · DirectorJun 24

1,279 sh @ $314.90 · -28.7% own

SSELL◷$158.1K

DeSimone Jill · DirectorJun 24

504 sh @ $313.66 · -10.2% own

SSELL◷$314.1K

DeSimone Jill · DirectorJun 24

1,004 sh @ $312.83 · -16.8% own

SSELL◷$890.2K

DeSimone Jill · DirectorJun 24

2,854 sh @ $311.91 · -32.4% own

SSELL◷$544.1K

DeSimone Jill · DirectorJun 24

1,750 sh @ $310.89 · -16.6% own

SSELL◷$309.1K

DeSimone Jill · DirectorJun 24

999 sh @ $309.38 · -8.6% own

SSELL◷$382.2K

DeSimone Jill · DirectorJun 24

1,240 sh @ $308.24 · -9.7% own

SSELL◷$209.5K

DeSimone Jill · DirectorJun 24

683 sh @ $306.77 · -5.1% own

SSELL◷$97.7K

DeSimone Jill · DirectorJun 24

320 sh @ $305.31 · -2.3% own

SSELL◷$36.4K

DeSimone Jill · DirectorJun 24

120 sh @ $303.13 · -0.9% own

SSELL◷$3K

DeSimone Jill · DirectorJun 24

10 sh @ $301.44 · <0.1% own

MEXER◷$446.9K

DeSimone Jill · DirectorJun 24

3,034 sh @ $147.30 · +27.8% own

MEXER◷$379K

DeSimone Jill · DirectorJun 24

8,566 sh @ $44.25 · +366.5% own

AGRANT◆—

Young William D · DirectorJun 10

648 sh

AGRANT—

Young William D · DirectorJun 10

1,371 sh · +72.2% own

AGRANT◆—

Norden Gregory · DirectorJun 10

648 sh

AGRANT—

Norden Gregory · DirectorJun 10

1,371 sh · +729.3% own

AGRANT◆—

Mitchell Dean J · DirectorJun 10

648 sh

AGRANT—

Mitchell Dean J · DirectorJun 10

1,371 sh · +8.0% own

AGRANT◆—

Kindler Jeffrey B · DirectorJun 10

648 sh

AGRANT—

Kindler Jeffrey B · DirectorJun 10

1,371 sh · +117.6% own

AGRANT◆—

DeSimone Jill · DirectorJun 10

648 sh

AGRANT—

DeSimone Jill · DirectorJun 10

1,371 sh · +141.9% own

AGRANT◆—

Cudkowicz Merit Ester · DirectorJun 10

648 sh

AGRANT—

Cudkowicz Merit Ester · DirectorJun 10

1,371 sh

AGRANT◆—

Chodakewitz Jeffrey · DirectorJun 10

648 sh

AGRANT—

Chodakewitz Jeffrey · DirectorJun 10

1,371 sh

AGRANT◆—

Arbuckle Stuart A · DirectorJun 10

648 sh

AGRANT—

Arbuckle Stuart A · DirectorJun 10

1,371 sh · +117.6% own

AGRANT$14.9K

Sniecinski Megan · Chief Operating…May 14

89 sh @ $167.94 · +0.3% own

AGRANT$21.2K

Souza Marcio · Chief Executive…May 14

126 sh @ $167.94 · +0.2% own

AGRANT$13.1K

Nemiroff Alex · General Counsel…May 14

78 sh @ $167.94 · +0.3% own

AGRANT$21.3K

Mastrocola Lauren · Principal Accounti…May 14

127 sh @ $167.94 · +0.9% own

AGRANT$20.3K

Kelly Timothy Edwin · Chief Financial…May 14

121 sh @ $167.94 · +0.4% own

AGRANT◆—

Kindler Jeffrey B · DirectorFeb 6

224 sh

AGRANT—

Kindler Jeffrey B · DirectorFeb 6

478 sh · +69.5% own

AGRANT—

Kindler Jeffrey B · DirectorFeb 6

688 sh

AGRANT◆—

Arbuckle Stuart A · DirectorFeb 6

224 sh

AGRANT—

Arbuckle Stuart A · DirectorFeb 6

478 sh · +69.5% own

AGRANT—

Arbuckle Stuart A · DirectorFeb 6

688 sh

FTAX$244K

Sniecinski Megan · Chief Operating…Jan 12

885 sh @ $275.74 · -3.0% own

FTAX$211.8K

Nemiroff Alex · General Counsel…Jan 12

768 sh @ $275.74 · -2.9% own

FTAX$94.9K

Mastrocola Lauren · Principal Accounti…Jan 12

344 sh @ $275.74 · -2.5% own

FTAX$260K

Kelly Timothy Edwin · Chief Financial…Jan 12

943 sh @ $275.74 · -2.9% own

FTAX$313.5K

Sniecinski Megan · Chief Operating…Jan 10

1,087 sh @ $288.45 · -3.6% own

FTAX$1.2M

Souza Marcio · Chief Executive…Jan 10

4,252 sh @ $288.45 · -5.2% own

FTAX$264.5K

Nemiroff Alex · General Counsel…Jan 10

917 sh @ $288.45 · -3.3% own

FTAX$105.9K

Mastrocola Lauren · Principal Accounti…Jan 10

367 sh @ $288.45 · -2.6% own

FTAX$385.1K

Kelly Timothy Edwin · Chief Financial…Jan 10

1,335 sh @ $288.45 · -4.0% own

AGRANT◆—

Sniecinski Megan · Chief Operating…Jan 8

7,700 sh

AGRANT—

Sniecinski Megan · Chief Operating…Jan 8

9,625 sh · +46.1% own

AGRANT◆—

Souza Marcio · Chief Executive…Jan 8

22,110 sh

AGRANT—

Souza Marcio · Chief Executive…Jan 8

27,640 sh · +51.7% own

AGRANT◆—

Nemiroff Alex · General Counsel…Jan 8

5,500 sh

AGRANT—

Nemiroff Alex · General Counsel…Jan 8

6,875 sh · +33.1% own

AGRANT◆—

Mastrocola Lauren · Principal Accounti…Jan 8

7,500 sh

AGRANT—

Mastrocola Lauren · Principal Accounti…Jan 8

3,750 sh · +36.0% own

AGRANT◆—

Kelly Timothy Edwin · Chief Financial…Jan 8

7,040 sh

AGRANT—

Kelly Timothy Edwin · Chief Financial…Jan 8

8,800 sh · +35.9% own

FTAX$118.5K

Souza Marcio · Chief Executive…Jan 7

405 sh @ $292.63 · -0.8% own

FTAX$26K

Nemiroff Alex · General Counsel…Jan 7

89 sh @ $292.63 · -0.4% own

FTAX$10.2K

Mastrocola Lauren · Principal Accounti…Jan 7

35 sh @ $292.63 · -0.3% own

FTAX$40.7K

Kelly Timothy Edwin · Chief Financial…Jan 7

139 sh @ $292.63 · -0.6% own

GGIFT—

Souza Marcio · Chief Executive…Dec 30, 2025

400 sh · -13.3% own

MEXER◆—