OKUR

OnKure Therapeutics, Inc.

Insider trading activity for OnKure Therapeutics, Inc., straight from SEC Form 4 filings. Net figures below count open-market buys and sales only — grants, option exercises and tax withholding are excluded because they are compensation, not decisions to trade.

Past 3 months

-$1.2K

net selling

Bought(0 · 0 insiders): $0
Sold(2 · 2 insiders): $1.2K

Past 6 months

-$2.9K

net selling

Bought(0 · 0 insiders): $0
Sold(4 · 2 insiders): $2.9K

Past 12 months

-$5.6K

net selling

Bought(0 · 0 insiders): $0
Sold(8 · 2 insiders): $5.6K

Transaction history

The 71 most recent Form 4 transactions.

Open in screener →

Insider transactions, newest first: date, security, transaction type, size and a link to the filing each row came from.
Date	Insider	Role	Type	Shares	Price	Value	Δ Own	Filing
Sep 21	Saccomano Nicholas A	President and CEO	SSELL	87	$2.97	$259	-0.8%	Open the original filing on SEC.gov
Sep 21	Leverone Jason A.	Chief Financial Officer	SSELL	302	$2.97	$898	-1.6%	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	AGRANT◆	542,232	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	DTOISS◆	542,232	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	AGRANT◆	16,898	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	DTOISS◆	16,898	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	AGRANT◆	8,449	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	DTOISS◆	8,449	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	AGRANT◆	1,485	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	DTOISS◆	1,485	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	AGRANT◆	2,359	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	DTOISS◆	2,359	—	—	—	Open the original filing on SEC.gov
Aug 7	Saccomano Nicholas A	President and CEO	AGRANT◆	150,000	—	—	—	Open the original filing on SEC.gov
Aug 7	Leverone Jason A.	Chief Financial Officer	AGRANT◆	130,611	—	—	—	Open the original filing on SEC.gov
Aug 7	Leverone Jason A.	Chief Financial Officer	DTOISS◆	130,611	—	—	—	Open the original filing on SEC.gov
Aug 7	Leverone Jason A.	Chief Financial Officer	AGRANT◆	5,322	—	—	—	Open the original filing on SEC.gov
Aug 7	Leverone Jason A.	Chief Financial Officer	DTOISS◆	5,322	—	—	—	Open the original filing on SEC.gov
Aug 7	Leverone Jason A.	Chief Financial Officer	AGRANT◆	5,781	—	—	—	Open the original filing on SEC.gov
Aug 7	Leverone Jason A.	Chief Financial Officer	DTOISS◆	5,781	—	—	—	Open the original filing on SEC.gov
Aug 7	Leverone Jason A.	Chief Financial Officer	AGRANT◆	50,000	—	—	—	Open the original filing on SEC.gov
Aug 7	Hartley Dylan	Chief Scientific Officer	AGRANT◆	137,603	—	—	—	Open the original filing on SEC.gov
Aug 7	Hartley Dylan	Chief Scientific Officer	DTOISS◆	137,603	—	—	—	Open the original filing on SEC.gov
Aug 7	Hartley Dylan	Chief Scientific Officer	AGRANT◆	50,000	—	—	—	Open the original filing on SEC.gov
Aug 7	Agresta Samuel	Chief Medical Officer	AGRANT◆	131,396	—	—	—	Open the original filing on SEC.gov
Aug 7	Agresta Samuel	Chief Medical Officer	DTOISS◆	131,396	—	—	—	Open the original filing on SEC.gov
Aug 7	Agresta Samuel	Chief Medical Officer	AGRANT◆	18,588	—	—	—	Open the original filing on SEC.gov
Aug 7	Agresta Samuel	Chief Medical Officer	DTOISS◆	18,588	—	—	—	Open the original filing on SEC.gov
Aug 7	Agresta Samuel	Chief Medical Officer	AGRANT◆	50,000	—	—	—	Open the original filing on SEC.gov
Aug 7	Mathers Edward T	Director	AGRANT◆	22,350	—	—	—	Open the original filing on SEC.gov
Aug 7	Phillips Andrew John	Director	AGRANT◆	22,350	—	—	—	Open the original filing on SEC.gov
Aug 7	Ratcliffe Liam	Director	AGRANT◆	22,350	—	—	—	Open the original filing on SEC.gov
Aug 7	Carruthers R Michael	Director	AGRANT◆	22,350	—	—	—	Open the original filing on SEC.gov
Aug 7	Jansen Valerie Malyvanh	Director	AGRANT◆	22,350	—	—	—	Open the original filing on SEC.gov
Aug 7	Grey Michael G	Director	AGRANT◆	22,350	—	—	—	Open the original filing on SEC.gov
Jun 22	Saccomano Nicholas A	President and CEO	SSELL	86	$4.40	$378	-0.8%	Open the original filing on SEC.gov
Jun 22	Leverone Jason A.	Chief Financial Officer	SSELL	303	$4.40	$1.3K	-1.6%	Open the original filing on SEC.gov
Jun 4	Phillips Andrew John	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
Jun 4	Ratcliffe Liam	Director	AGRANT◆	1,275	—	—	—	Open the original filing on SEC.gov
Jun 4	Mathers Edward T	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
Jun 4	Jansen Valerie Malyvanh	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
Jun 4	Grey Michael G	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
Jun 4	Carruthers R Michael	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
Apr 1	Saccomano Nicholas A	President and CEO	AGRANT◆	330,000	—	—	—	Open the original filing on SEC.gov
Apr 1	Leverone Jason A.	Chief Financial Officer	AGRANT◆	110,000	—	—	—	Open the original filing on SEC.gov
Apr 1	Hartley Dylan	Chief Scientific Officer	AGRANT◆	110,000	—	—	—	Open the original filing on SEC.gov
Apr 1	Agresta Samuel	Chief Medical Officer	AGRANT◆	110,000	—	—	—	Open the original filing on SEC.gov
Mar 31	Ratcliffe Liam	Director	AGRANT◆	15,300	—	—	—	Open the original filing on SEC.gov
Mar 23	Saccomano Nicholas A	President and CEO	SSELL	86	$4.16	$357	-1.2%	Open the original filing on SEC.gov
Mar 23	Leverone Jason A.	Chief Financial Officer	SSELL	301	$4.16	$1.3K	-1.8%	Open the original filing on SEC.gov
Dec 31, 2025	Mathers Edward T	Director	AGRANT	3,911	—	—	+34.3%	Open the original filing on SEC.gov
Dec 31, 2025	Manke Isaac	Director	AGRANT	5,258	—	—	+34.3%	Open the original filing on SEC.gov
Dec 22, 2025	Saccomano Nicholas A	President and CEO	SSELL	87	$2.97	$258	-1.2%	Open the original filing on SEC.gov
Dec 22, 2025	Leverone Jason A.	Chief Financial Officer	SSELL	302	$2.97	$896	-1.8%	Open the original filing on SEC.gov
Sep 30, 2025	Mathers Edward T	Director	AGRANT	4,125	—	—	+56.7%	Open the original filing on SEC.gov
Sep 30, 2025	Manke Isaac	Director	AGRANT	5,545	—	—	+56.7%	Open the original filing on SEC.gov
Sep 22, 2025	Saccomano Nicholas A	President and CEO	SSELL	88	$2.62	$231	-2.5%	Open the original filing on SEC.gov
Sep 22, 2025	Leverone Jason A.	Chief Financial Officer	SSELL	303	$2.62	$795	-2.4%	Open the original filing on SEC.gov
Jun 30, 2025	Mathers Edward T	Director	AGRANT	4,694	—	—	+181.9%	Open the original filing on SEC.gov
Jun 30, 2025	Manke Isaac	Director	AGRANT	6,311	—	—	+181.9%	Open the original filing on SEC.gov
Jun 23, 2025	Saccomano Nicholas A	President and CEO	SSELL	88	$2.38	$210	-2.4%	Open the original filing on SEC.gov
Jun 23, 2025	Leverone Jason A.	Chief Financial Officer	SSELL	303	$2.38	$722	-2.3%	Open the original filing on SEC.gov
May 28, 2025	Phillips Andrew John	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
May 28, 2025	Mathers Edward T	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
May 28, 2025	Manke Isaac	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
May 28, 2025	Jansen Valerie Malyvanh	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
May 28, 2025	Grey Michael G	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
May 28, 2025	Carruthers R Michael	Director	AGRANT◆	7,650	—	—	—	Open the original filing on SEC.gov
May 15, 2025	Cormorant Asset…	Former 10% Owner	SSELL	1.8M	$1.85	$3.4M	-100.0%	Open the original filing on SEC.gov
May 15, 2025	Acorn Bioventures, L.p.	10% Owner	PBUY▲	1.1M	$1.85	$2.1M	—	Open the original filing on SEC.gov
May 15, 2025	Acorn Bioventures, L.p.	10% Owner	PBUY	270,270	$1.85	$500K	+18.8%	Open the original filing on SEC.gov
May 12, 2025	Cormorant Asset…	10% Owner	SSELL	24,300	$1.99	$48.2K	-1.3%	Open the original filing on SEC.gov

SSELL$259

Saccomano Nicholas A · President and CEOSep 21

87 sh @ $2.97 · -0.8% own

SSELL$898

Leverone Jason A. · Chief Financial…Sep 21

302 sh @ $2.97 · -1.6% own

AGRANT◆—

Saccomano Nicholas A · President and CEOAug 7

542,232 sh

DTOISS◆—

Saccomano Nicholas A · President and CEOAug 7

542,232 sh

AGRANT◆—

Saccomano Nicholas A · President and CEOAug 7

16,898 sh

DTOISS◆—

Saccomano Nicholas A · President and CEOAug 7

16,898 sh

AGRANT◆—

Saccomano Nicholas A · President and CEOAug 7

8,449 sh

DTOISS◆—

Saccomano Nicholas A · President and CEOAug 7

8,449 sh

AGRANT◆—

Saccomano Nicholas A · President and CEOAug 7

1,485 sh

DTOISS◆—

Saccomano Nicholas A · President and CEOAug 7

1,485 sh

AGRANT◆—

Saccomano Nicholas A · President and CEOAug 7

2,359 sh

DTOISS◆—

Saccomano Nicholas A · President and CEOAug 7

2,359 sh

AGRANT◆—

Saccomano Nicholas A · President and CEOAug 7

150,000 sh

AGRANT◆—

Leverone Jason A. · Chief Financial…Aug 7

130,611 sh

DTOISS◆—

Leverone Jason A. · Chief Financial…Aug 7

130,611 sh

AGRANT◆—

Leverone Jason A. · Chief Financial…Aug 7

5,322 sh

DTOISS◆—

Leverone Jason A. · Chief Financial…Aug 7

5,322 sh

AGRANT◆—

Leverone Jason A. · Chief Financial…Aug 7

5,781 sh

DTOISS◆—

Leverone Jason A. · Chief Financial…Aug 7

5,781 sh

AGRANT◆—

Leverone Jason A. · Chief Financial…Aug 7

50,000 sh

AGRANT◆—

Hartley Dylan · Chief Scientific…Aug 7

137,603 sh

DTOISS◆—

Hartley Dylan · Chief Scientific…Aug 7

137,603 sh

AGRANT◆—

Hartley Dylan · Chief Scientific…Aug 7

50,000 sh

AGRANT◆—

Agresta Samuel · Chief Medical…Aug 7

131,396 sh

DTOISS◆—

Agresta Samuel · Chief Medical…Aug 7

131,396 sh

AGRANT◆—

Agresta Samuel · Chief Medical…Aug 7

18,588 sh

DTOISS◆—

Agresta Samuel · Chief Medical…Aug 7

18,588 sh

AGRANT◆—

Agresta Samuel · Chief Medical…Aug 7

50,000 sh

AGRANT◆—

Mathers Edward T · DirectorAug 7

22,350 sh

AGRANT◆—

Phillips Andrew John · DirectorAug 7

22,350 sh

AGRANT◆—

Ratcliffe Liam · DirectorAug 7

22,350 sh

AGRANT◆—

Carruthers R Michael · DirectorAug 7

22,350 sh

AGRANT◆—

Jansen Valerie Malyvanh · DirectorAug 7

22,350 sh

AGRANT◆—

Grey Michael G · DirectorAug 7

22,350 sh

SSELL$378

Saccomano Nicholas A · President and CEOJun 22

86 sh @ $4.40 · -0.8% own

SSELL$1.3K

Leverone Jason A. · Chief Financial…Jun 22

303 sh @ $4.40 · -1.6% own

AGRANT◆—

Phillips Andrew John · DirectorJun 4

7,650 sh

AGRANT◆—

Ratcliffe Liam · DirectorJun 4

1,275 sh

AGRANT◆—

Mathers Edward T · DirectorJun 4

7,650 sh

AGRANT◆—

Jansen Valerie Malyvanh · DirectorJun 4

7,650 sh

AGRANT◆—

Grey Michael G · DirectorJun 4

7,650 sh

AGRANT◆—

Carruthers R Michael · DirectorJun 4

7,650 sh

AGRANT◆—

Saccomano Nicholas A · President and CEOApr 1

330,000 sh

AGRANT◆—

Leverone Jason A. · Chief Financial…Apr 1

110,000 sh

AGRANT◆—

Hartley Dylan · Chief Scientific…Apr 1

110,000 sh

AGRANT◆—

Agresta Samuel · Chief Medical…Apr 1

110,000 sh

AGRANT◆—

Ratcliffe Liam · DirectorMar 31

15,300 sh

SSELL$357

Saccomano Nicholas A · President and CEOMar 23

86 sh @ $4.16 · -1.2% own

SSELL$1.3K

Leverone Jason A. · Chief Financial…Mar 23

301 sh @ $4.16 · -1.8% own

AGRANT—

Mathers Edward T · DirectorDec 31, 2025

3,911 sh · +34.3% own

AGRANT—

Manke Isaac · DirectorDec 31, 2025

5,258 sh · +34.3% own

SSELL$258

Saccomano Nicholas A · President and CEODec 22, 2025

87 sh @ $2.97 · -1.2% own

SSELL$896

Leverone Jason A. · Chief Financial…Dec 22, 2025

302 sh @ $2.97 · -1.8% own

AGRANT—

Mathers Edward T · DirectorSep 30, 2025

4,125 sh · +56.7% own

AGRANT—

Manke Isaac · DirectorSep 30, 2025

5,545 sh · +56.7% own

SSELL$231

Saccomano Nicholas A · President and CEOSep 22, 2025

88 sh @ $2.62 · -2.5% own

SSELL$795

Leverone Jason A. · Chief Financial…Sep 22, 2025

303 sh @ $2.62 · -2.4% own

AGRANT—

Mathers Edward T · DirectorJun 30, 2025

4,694 sh · +181.9% own

AGRANT—

Manke Isaac · DirectorJun 30, 2025

6,311 sh · +181.9% own

SSELL$210

Saccomano Nicholas A · President and CEOJun 23, 2025

88 sh @ $2.38 · -2.4% own

SSELL$722

Leverone Jason A. · Chief Financial…Jun 23, 2025

303 sh @ $2.38 · -2.3% own

AGRANT◆—

Phillips Andrew John · DirectorMay 28, 2025

7,650 sh

AGRANT◆—

Mathers Edward T · DirectorMay 28, 2025

7,650 sh

AGRANT◆—

Manke Isaac · DirectorMay 28, 2025

7,650 sh

AGRANT◆—

Jansen Valerie Malyvanh · DirectorMay 28, 2025

7,650 sh

AGRANT◆—

Grey Michael G · DirectorMay 28, 2025

7,650 sh

AGRANT◆—

Carruthers R Michael · DirectorMay 28, 2025

7,650 sh

SSELL$3.4M

Cormorant Asset… · Former 10% OwnerMay 15, 2025

1.8M sh @ $1.85 · -100.0% own

PBUY▲$2.1M

Acorn Bioventures, L.p. · 10% OwnerMay 15, 2025

1.1M sh @ $1.85

PBUY$500K

Acorn Bioventures, L.p. · 10% OwnerMay 15, 2025

270,270 sh @ $1.85 · +18.8% own

SSELL$48.2K

Cormorant Asset… · 10% OwnerMay 12, 2025

24,300 sh @ $1.99 · -1.3% own

Filing record

How quickly insiders here report their trades. Section 16 allows two business days from the transaction.

All 48 filings we hold were filed within the two-business-day deadline.

Counted in business days from the transaction date, or the deemed execution date where the filing reports one, excluding weekends and federal holidays. How this is measured · All late filings

Insiders at this company

Everyone who has filed a Form 4 for this issuer.

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