| Aug 29, 2025 | Rhoads Ann D | Director | DTOISS◆ | 27,178 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | McGrath Yvonne | Chief Scientific Officer | DTOISS◆ | 16,054 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | McGrath Yvonne | Chief Scientific Officer | DTOISS◆ | 69,069 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | McGrath Yvonne | Chief Scientific Officer | DTOISS◆ | 91,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | McGrath Yvonne | Chief Scientific Officer | UTENDR | 46,300 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Lee David K | Director | DTOISS◆ | 23,625 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Lee David K | Director | DTOISS◆ | 21,141 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Hallal David | Director | DTOISS◆ | 146,160 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Hallal David | Director | DTOISS◆ | 25,140 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | DTOISS◆ | 252,135 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | DTOISS◆ | 8,123 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | DTOISS◆ | 42,388 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | DTOISS◆ | 135,937 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | DTOISS◆ | 9,063 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | UTENDR | 89,429 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Feltquate David | Chief Medical Officer | UTENDR | 47,000 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | DTOISS◆ | 52,700 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | DTOISS◆ | 185,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | DTOISS◆ | 17,544 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | DTOISS◆ | 50,128 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | DTOISS◆ | 94,336 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | DTOISS◆ | 444,815 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | DTOISS◆ | 14,185 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | UTENDR | 94,027 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer | UTENDR | 153,903 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | DTOISS◆ | 146,835 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | DTOISS◆ | 17,074 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | DTOISS◆ | 66,170 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | DTOISS◆ | 41,694 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | DTOISS◆ | 135,937 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | DTOISS◆ | 9,063 | — | — | — | ↗Open the original filing on SEC.gov |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | UTENDR | 161,898 | — | — | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 94,027 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 18,000 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 43,883 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 8,400 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 94,027 | $4.30 | $404.3K | — | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 18,000 | $4.30 | $77.4K | +13.2% | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 43,883 | $10.02 | $439.7K | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 43,883 | $4.30 | $188.7K | — | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 8,400 | $10.02 | $84.2K | -5.8% | ↗Open the original filing on SEC.gov |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 8,400 | $4.30 | $36.1K | +6.2% | ↗Open the original filing on SEC.gov |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 43,882 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 8,400 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 43,882 | $10.03 | $440.1K | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 43,882 | $4.30 | $188.7K | — | ↗Open the original filing on SEC.gov |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 8,400 | $10.03 | $84.3K | -5.8% | ↗Open the original filing on SEC.gov |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 8,400 | $4.30 | $36.1K | +6.2% | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Hallal David | Director | MEXER◷◆ | 38,228 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Hallal David | Director | SSELL◷ | 38,228 | $10.24 | $391.5K | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Hallal David | Director | MEXER◷ | 38,228 | $4.30 | $164.4K | — | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 43,882 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 8,400 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 43,882 | $10.21 | $448K | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 43,882 | $4.30 | $188.7K | — | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 8,400 | $10.21 | $85.8K | -5.8% | ↗Open the original filing on SEC.gov |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 8,400 | $4.30 | $36.1K | +6.2% | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Hallal David | Director | MEXER◷◆ | 38,227 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Hallal David | Director | SSELL◷ | 38,227 | $10.15 | $388K | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Hallal David | Director | MEXER◷ | 38,227 | $4.30 | $164.4K | — | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 43,882 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 8,400 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 43,882 | $10.15 | $445.4K | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 43,882 | $4.30 | $188.7K | — | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 8,400 | $10.15 | $85.3K | -5.8% | ↗Open the original filing on SEC.gov |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 8,400 | $4.30 | $36.1K | +6.2% | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Hallal David | Director | MEXER◷◆ | 38,227 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Hallal David | Director | SSELL◷ | 38,227 | $10.07 | $384.9K | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Hallal David | Director | MEXER◷ | 38,227 | $4.30 | $164.4K | — | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 43,883 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷◆ | 8,400 | — | — | — | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 43,883 | $10.10 | $443.2K | -100.0% | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 43,883 | $4.30 | $188.7K | — | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | SSELL◷ | 8,400 | $10.10 | $84.8K | -5.8% | ↗Open the original filing on SEC.gov |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | MEXER◷ | 8,400 | $4.30 | $36.1K | +6.2% | ↗Open the original filing on SEC.gov |
| May 15, 2025 | EcoR1 Capital, LLC | 10% Owner | PBUY | 3.3M | $8.00 | $26.4M | +44.7% | ↗Open the original filing on SEC.gov |
| May 14, 2025 | EcoR1 Capital, LLC | 10% Owner | PBUY | 1.7M | $7.41 | $12.3M | +28.9% | ↗Open the original filing on SEC.gov |
| May 13, 2025 | Van Hauwermeiren Timothy | Director | MEXER◆ | 22,346 | — | — | — | ↗Open the original filing on SEC.gov |
| May 13, 2025 | Van Hauwermeiren Timothy | Director | MEXER | 22,346 | $4.30 | $96.1K | — | ↗Open the original filing on SEC.gov |
| May 13, 2025 | Mpm Bioventures 2018,… | Former 10% Owner | SSELL | 630,191 | $8.06 | $5.1M | -23.0% | ↗Open the original filing on SEC.gov |
| May 13, 2025 | Gadicke Ansbert | Former 10% Owner | SSELL | 1M | $8.06 | $8.3M | -23.0% | ↗Open the original filing on SEC.gov |
| May 13, 2025 | MPM BioVentures 2014,… | Former 10% Owner | SSELL | 630,191 | $8.06 | $5.1M | -23.0% | ↗Open the original filing on SEC.gov |