DFTX

Definium Therapeutics, Inc.

Insider trading activity for Definium Therapeutics, Inc., straight from SEC Form 4 filings. Net figures below count open-market buys and sales only — grants, option exercises and tax withholding are excluded because they are compensation, not decisions to trade.

Past 3 months

-$721.7K

net selling

Bought(0 · 0 insiders): $0
Sold(1 · 1 insiders): $721.7K

Past 6 months

-$3.3M

net selling

Bought(0 · 0 insiders): $0
Sold(6 · 5 insiders): $3.3M

Past 12 months

-$4.7M

net selling

Bought(0 · 0 insiders): $0
Sold(12 · 5 insiders): $4.7M

Transaction history

The 62 most recent Form 4 transactions.

Open in screener →

Insider transactions, newest first: date, security, transaction type, size and a link to the filing each row came from.
Date	Insider	Role	Type	Shares	Price	Value	Δ Own	Filing
Sep 18	Krebs Andreas	Director	MEXER◆	1,629	—	—	—	Open the original filing on SEC.gov
Sep 18	Krebs Andreas	Director	MEXER	1,629	$35.52	$57.9K	+8.2%	Open the original filing on SEC.gov
Sep 18	Vallone Carol A	Director	MEXER◆	1,086	—	—	—	Open the original filing on SEC.gov
Sep 18	Vallone Carol A	Director	MEXER	1,086	$35.52	$38.6K	+5.1%	Open the original filing on SEC.gov
Sep 14	Barrow Robert	Chief Executive Officer	AGRANT	750,000	—	—	+50.2%	Open the original filing on SEC.gov
Sep 14	Roberts Brandi	Chief Financial Officer	AGRANT	125,000	—	—	+45.8%	Open the original filing on SEC.gov
Sep 14	Sullivan Mark	Chief Legal Officer	AGRANT	125,000	—	—	+32.6%	Open the original filing on SEC.gov
Sep 14	Wiley Matthew T.	Chief Commercial Officer	AGRANT	125,000	—	—	+52.7%	Open the original filing on SEC.gov
Sep 14	Karlin Daniel	Chief Medical Officer	AGRANT	200,000	—	—	+33.1%	Open the original filing on SEC.gov
Sep 3	Barrow Robert	Chief Executive Officer	SSELL◷	19,023	$37.94	$721.7K	-1.3%	Open the original filing on SEC.gov
Sep 2	Barrow Robert	Chief Executive Officer	AGRANT◷	40,000	—	—	+2.7%	Open the original filing on SEC.gov
Aug 12	Roberts Brandi	Chief Financial Officer	AGRANT	62,500	—	—	+29.8%	Open the original filing on SEC.gov
Aug 12	Wiley Matthew T.	Chief Commercial Officer	AGRANT	62,500	—	—	+35.8%	Open the original filing on SEC.gov
Aug 12	Sullivan Mark	Chief Legal Officer	AGRANT	62,500	—	—	+19.5%	Open the original filing on SEC.gov
Aug 12	Karlin Daniel	Chief Medical Officer	AGRANT	100,000	—	—	+19.9%	Open the original filing on SEC.gov
Aug 12	Barrow Robert	Chief Executive Officer	AGRANT	375,000	—	—	+34.2%	Open the original filing on SEC.gov
Jun 25	Sullivan Mark	Chief Legal Officer	SSELL◷	13,008	$45.03	$585.8K	-3.9%	Open the original filing on SEC.gov
Jun 25	Karlin Daniel	Chief Medical Officer	SSELL◷	10,035	$45.03	$451.9K	-1.9%	Open the original filing on SEC.gov
Jun 25	Roberts Brandi	Chief Financial Officer	SSELL◷	3,013	$45.03	$135.7K	-1.4%	Open the original filing on SEC.gov
Jun 25	Wiley Matthew T.	Chief Commercial Officer	SSELL◷	2,867	$45.03	$129.1K	-1.6%	Open the original filing on SEC.gov
Jun 25	Barrow Robert	Chief Executive Officer	SSELL◷	29,208	$45.03	$1.3M	-2.6%	Open the original filing on SEC.gov
Jun 22	Wiley Matthew T.	Chief Commercial Officer	AGRANT	62,500	—	—	+54.4%	Open the original filing on SEC.gov
Jun 22	Roberts Brandi	Chief Financial Officer	AGRANT	62,500	—	—	+41.7%	Open the original filing on SEC.gov
Jun 22	Sullivan Mark	Chief Legal Officer	AGRANT	62,500	—	—	+23.1%	Open the original filing on SEC.gov
Jun 22	Karlin Daniel	Chief Medical Officer	AGRANT	100,000	—	—	+24.2%	Open the original filing on SEC.gov
Jun 22	Barrow Robert	Chief Executive Officer	AGRANT	375,000	—	—	+49.8%	Open the original filing on SEC.gov
Jun 11	Gryska David W	Director	AGRANT◆	19,188	—	—	—	Open the original filing on SEC.gov
Jun 11	Gryska David W	Director	AGRANT	4,666	—	—	+30.6%	Open the original filing on SEC.gov
Jun 11	Vallone Carol A	Director	AGRANT◆	19,188	—	—	—	Open the original filing on SEC.gov
Jun 11	Vallone Carol A	Director	AGRANT	4,666	—	—	+28.2%	Open the original filing on SEC.gov
Jun 11	Krebs Andreas	Director	AGRANT◆	19,188	—	—	—	Open the original filing on SEC.gov
Jun 11	Krebs Andreas	Director	AGRANT	4,666	—	—	+30.9%	Open the original filing on SEC.gov
Jun 11	Crystal Roger	Director	AGRANT◆	19,188	—	—	—	Open the original filing on SEC.gov
Jun 11	Crystal Roger	Director	AGRANT	4,666	—	—	+23.8%	Open the original filing on SEC.gov
Jun 11	Bruhn Suzanne Louise	Director	AGRANT◆	19,188	—	—	—	Open the original filing on SEC.gov
Jun 11	Bruhn Suzanne Louise	Director	AGRANT	4,666	—	—	+23.8%	Open the original filing on SEC.gov
Jun 11	Adsett Roger	Director	AGRANT◆	14,620	—	—	—	Open the original filing on SEC.gov
Jun 11	Adsett Roger	Director	AGRANT	3,555	—	—	—	Open the original filing on SEC.gov
Mar 25	Karlin Daniel	Chief Medical Officer	SSELL◷	8,018	$18.47	$148.1K	-1.9%	Open the original filing on SEC.gov
Mar 25	Sullivan Mark	Chief Legal Officer	SSELL◷	10,702	$18.47	$197.7K	-3.8%	Open the original filing on SEC.gov
Mar 25	Barrow Robert	Chief Executive Officer	SSELL◷	24,431	$18.47	$451.2K	-3.1%	Open the original filing on SEC.gov
Feb 3	Wiley Matthew T.	Chief Commercial Officer	AGRANT	115,000	—	—	—	Open the original filing on SEC.gov
Feb 3	Roberts Brandi	Chief Financial Officer	AGRANT	150,000	—	—	—	Open the original filing on SEC.gov
Feb 3	Sullivan Mark	Chief Legal Officer	AGRANT	125,000	—	—	+44.2%	Open the original filing on SEC.gov
Feb 3	Karlin Daniel	Chief Medical Officer	AGRANT	150,000	—	—	+35.3%	Open the original filing on SEC.gov
Feb 3	Barrow Robert	Chief Executive Officer	AGRANT	320,000	—	—	+41.1%	Open the original filing on SEC.gov
Jan 29	Adsett Roger	Director	AGRANT◆	50,000	—	—	—	Open the original filing on SEC.gov
Dec 26, 2025	Sullivan Mark	Chief Legal Officer	SSELL◷	11,276	$13.15	$148.2K	-3.8%	Open the original filing on SEC.gov
Dec 26, 2025	Karlin Daniel	Chief Medical Officer	SSELL◷	5,600	$13.15	$73.6K	-1.3%	Open the original filing on SEC.gov
Dec 26, 2025	Barrow Robert	Chief Executive Officer	SSELL◷	25,791	$13.15	$339.1K	-3.2%	Open the original filing on SEC.gov
Sep 25, 2025	Sullivan Mark	Chief Legal Officer	SSELL◷	11,278	$9.77	$110.2K	-3.7%	Open the original filing on SEC.gov
Sep 25, 2025	Karlin Daniel	Chief Medical Officer	SSELL◷	7,704	$9.77	$75.3K	-1.8%	Open the original filing on SEC.gov
Sep 25, 2025	Barrow Robert	Chief Executive Officer	SSELL◷	25,797	$9.77	$252K	-3.1%	Open the original filing on SEC.gov
Jun 25, 2025	Sullivan Mark	Chief Legal Officer	SSELL◷	11,491	$6.80	$78.1K	-3.6%	Open the original filing on SEC.gov
Jun 25, 2025	Karlin Daniel	Chief Medical Officer	SSELL◷	7,848	$6.80	$53.4K	-1.8%	Open the original filing on SEC.gov
Jun 25, 2025	Barrow Robert	Chief Executive Officer	SSELL◷	26,491	$6.80	$180.1K	-3.1%	Open the original filing on SEC.gov
Jun 12, 2025	Vallone Carol A	Director	AGRANT◆	75,187	—	—	—	Open the original filing on SEC.gov
Jun 12, 2025	Krebs Andreas	Director	AGRANT◆	75,187	—	—	—	Open the original filing on SEC.gov
Jun 12, 2025	Gryska David W	Director	AGRANT◆	75,187	—	—	—	Open the original filing on SEC.gov
Jun 12, 2025	Crystal Roger	Director	AGRANT◆	75,187	—	—	—	Open the original filing on SEC.gov
Jun 12, 2025	Bruhn Suzanne Louise	Director	AGRANT◆	75,187	—	—	—	Open the original filing on SEC.gov
Jun 2, 2025	Roberts Brandi	Chief Financial Officer	AGRANT◆	500,000	—	—	—	Open the original filing on SEC.gov

MEXER◆—

Krebs Andreas · DirectorSep 18

1,629 sh

MEXER$57.9K

Krebs Andreas · DirectorSep 18

1,629 sh @ $35.52 · +8.2% own

MEXER◆—

Vallone Carol A · DirectorSep 18

1,086 sh

MEXER$38.6K

Vallone Carol A · DirectorSep 18

1,086 sh @ $35.52 · +5.1% own

AGRANT—

Barrow Robert · Chief Executive…Sep 14

750,000 sh · +50.2% own

AGRANT—

Roberts Brandi · Chief Financial…Sep 14

125,000 sh · +45.8% own

AGRANT—

Sullivan Mark · Chief Legal…Sep 14

125,000 sh · +32.6% own

AGRANT—

Wiley Matthew T. · Chief Commercial…Sep 14

125,000 sh · +52.7% own

AGRANT—

Karlin Daniel · Chief Medical…Sep 14

200,000 sh · +33.1% own

SSELL◷$721.7K

Barrow Robert · Chief Executive…Sep 3

19,023 sh @ $37.94 · -1.3% own

AGRANT◷—

Barrow Robert · Chief Executive…Sep 2

40,000 sh · +2.7% own

AGRANT—

Roberts Brandi · Chief Financial…Aug 12

62,500 sh · +29.8% own

AGRANT—

Wiley Matthew T. · Chief Commercial…Aug 12

62,500 sh · +35.8% own

AGRANT—

Sullivan Mark · Chief Legal…Aug 12

62,500 sh · +19.5% own

AGRANT—

Karlin Daniel · Chief Medical…Aug 12

100,000 sh · +19.9% own

AGRANT—

Barrow Robert · Chief Executive…Aug 12

375,000 sh · +34.2% own

SSELL◷$585.8K

Sullivan Mark · Chief Legal…Jun 25

13,008 sh @ $45.03 · -3.9% own

SSELL◷$451.9K

Karlin Daniel · Chief Medical…Jun 25

10,035 sh @ $45.03 · -1.9% own

SSELL◷$135.7K

Roberts Brandi · Chief Financial…Jun 25

3,013 sh @ $45.03 · -1.4% own

SSELL◷$129.1K

Wiley Matthew T. · Chief Commercial…Jun 25

2,867 sh @ $45.03 · -1.6% own

SSELL◷$1.3M

Barrow Robert · Chief Executive…Jun 25

29,208 sh @ $45.03 · -2.6% own

AGRANT—

Wiley Matthew T. · Chief Commercial…Jun 22

62,500 sh · +54.4% own

AGRANT—

Roberts Brandi · Chief Financial…Jun 22

62,500 sh · +41.7% own

AGRANT—

Sullivan Mark · Chief Legal…Jun 22

62,500 sh · +23.1% own

AGRANT—

Karlin Daniel · Chief Medical…Jun 22

100,000 sh · +24.2% own

AGRANT—

Barrow Robert · Chief Executive…Jun 22

375,000 sh · +49.8% own

AGRANT◆—

Gryska David W · DirectorJun 11

19,188 sh

AGRANT—

Gryska David W · DirectorJun 11

4,666 sh · +30.6% own

AGRANT◆—

Vallone Carol A · DirectorJun 11

19,188 sh

AGRANT—

Vallone Carol A · DirectorJun 11

4,666 sh · +28.2% own

AGRANT◆—

Krebs Andreas · DirectorJun 11

19,188 sh

AGRANT—

Krebs Andreas · DirectorJun 11

4,666 sh · +30.9% own

AGRANT◆—

Crystal Roger · DirectorJun 11

19,188 sh

AGRANT—

Crystal Roger · DirectorJun 11

4,666 sh · +23.8% own

AGRANT◆—

Bruhn Suzanne Louise · DirectorJun 11

19,188 sh

AGRANT—

Bruhn Suzanne Louise · DirectorJun 11

4,666 sh · +23.8% own

AGRANT◆—

Adsett Roger · DirectorJun 11

14,620 sh

AGRANT—

Adsett Roger · DirectorJun 11

3,555 sh

SSELL◷$148.1K

Karlin Daniel · Chief Medical…Mar 25

8,018 sh @ $18.47 · -1.9% own

SSELL◷$197.7K

Sullivan Mark · Chief Legal…Mar 25

10,702 sh @ $18.47 · -3.8% own

SSELL◷$451.2K

Barrow Robert · Chief Executive…Mar 25

24,431 sh @ $18.47 · -3.1% own

AGRANT—

Wiley Matthew T. · Chief Commercial…Feb 3

115,000 sh

AGRANT—

Roberts Brandi · Chief Financial…Feb 3

150,000 sh

AGRANT—

Sullivan Mark · Chief Legal…Feb 3

125,000 sh · +44.2% own

AGRANT—

Karlin Daniel · Chief Medical…Feb 3

150,000 sh · +35.3% own

AGRANT—

Barrow Robert · Chief Executive…Feb 3

320,000 sh · +41.1% own

AGRANT◆—

Adsett Roger · DirectorJan 29

50,000 sh

SSELL◷$148.2K

Sullivan Mark · Chief Legal…Dec 26, 2025

11,276 sh @ $13.15 · -3.8% own

SSELL◷$73.6K

Karlin Daniel · Chief Medical…Dec 26, 2025

5,600 sh @ $13.15 · -1.3% own

SSELL◷$339.1K

Barrow Robert · Chief Executive…Dec 26, 2025

25,791 sh @ $13.15 · -3.2% own

SSELL◷$110.2K

Sullivan Mark · Chief Legal…Sep 25, 2025

11,278 sh @ $9.77 · -3.7% own

SSELL◷$75.3K

Karlin Daniel · Chief Medical…Sep 25, 2025

7,704 sh @ $9.77 · -1.8% own

SSELL◷$252K

Barrow Robert · Chief Executive…Sep 25, 2025

25,797 sh @ $9.77 · -3.1% own

SSELL◷$78.1K

Sullivan Mark · Chief Legal…Jun 25, 2025

11,491 sh @ $6.80 · -3.6% own

SSELL◷$53.4K

Karlin Daniel · Chief Medical…Jun 25, 2025

7,848 sh @ $6.80 · -1.8% own

SSELL◷$180.1K

Barrow Robert · Chief Executive…Jun 25, 2025

26,491 sh @ $6.80 · -3.1% own

AGRANT◆—

Vallone Carol A · DirectorJun 12, 2025

75,187 sh

AGRANT◆—

Krebs Andreas · DirectorJun 12, 2025

75,187 sh

AGRANT◆—

Gryska David W · DirectorJun 12, 2025

75,187 sh

AGRANT◆—

Crystal Roger · DirectorJun 12, 2025

75,187 sh

AGRANT◆—

Bruhn Suzanne Louise · DirectorJun 12, 2025

75,187 sh

AGRANT◆—

Roberts Brandi · Chief Financial…Jun 2, 2025

500,000 sh

Filing record

How quickly insiders here report their trades. Section 16 allows two business days from the transaction.

All 46 filings we hold were filed within the two-business-day deadline.

Counted in business days from the transaction date, or the deemed execution date where the filing reports one, excluding weekends and federal holidays. How this is measured · All late filings

Insiders at this company

Everyone who has filed a Form 4 for this issuer.

More biotech & pharma companies

Other issuers in the same industry with insider filings on record.

Whole sector →